Recombinant Human NNMT, T7 -tagged
Cat.No. : | NNMT-27994TH |
Product Overview : | Recombinant full length protein, corresponding to Human NNMT fused with T7 tag at N-terminus. |
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Description : | N-methylation is one method by which drug and other xenobiotic compounds are metabolized by the liver. This gene encodes the protein responsible for this enzymatic activity which uses S-adenosyl methionine as the methyl donor. |
Conjugation : | T7 |
Source : | E. coli |
Tissue specificity : | Predominantly expressed in the liver. A lower expression is seen in the kidney, lung, skeletal muscle, placenta and heart. Not detected in the brain or pancreas. |
Form : | Liquid |
Purity : | >95% by SDS-PAGE |
Storage buffer : | Preservative: 0.002% Sodium AzideConstituents: 0.1% Triton-X-100, 10mM Tris, pH 8 |
Storage : | Aliquot and store at -80°C. Avoid repeated freeze / thaw cycles. |
Sequence Similarities : | Belongs to the NNMT/PNMT/TEMT family. |
Gene Name : | NNMT nicotinamide N-methyltransferase [ Homo sapiens ] |
Official Symbol : | NNMT |
Synonyms : | NNMT; nicotinamide N-methyltransferase; |
Gene ID : | 4837 |
mRNA Refseq : | NM_006169 |
Protein Refseq : | NP_006160 |
MIM : | 600008 |
Uniprot ID : | P40261 |
Chromosome Location : | 11q23.1 |
Pathway : | Biological oxidations, organism-specific biosystem; Metabolic pathways, organism-specific biosystem; Metabolism, organism-specific biosystem; Methylation, organism-specific biosystem; Nicotinate and nicotinamide metabolism, organism-specific biosystem; |
Function : | methyltransferase activity; nicotinamide N-methyltransferase activity; transferase activity; |
Products Types
◆ Recombinant Protein | ||
Nnmt-4449M | Recombinant Mouse Nnmt Protein, Myc/DDK-tagged | +Inquiry |
NNMT-034H | Recombinant Human NNMT Protein, His/SUMO-tagged | +Inquiry |
NNMT-780H | Recombinant Human NNMT Protein, His-tagged | +Inquiry |
NNMT-185H | Recombinant Human NNMT Protein, MYC/DDK-tagged, C13 and N15-labeled | +Inquiry |
NNMT-017H | Recombinant Human NNMT Protein, His/SUMO-tagged | +Inquiry |
◆ Lysates | ||
NNMT-3779HCL | Recombinant Human NNMT 293 Cell Lysate | +Inquiry |
◆ Assay kits | ||
Kit-2215 | N'-Nicotinamide Methyltransferase (NNMT) Inhibitor Screening Assay Kit | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (5)
Ask a questionYes, elevated levels of NNMT in blood or tissues have been proposed as potential biomarkers for certain diseases.
Elevated NNMT levels have been associated with increased risk of cardiovascular diseases, making it a potential therapeutic target.
Research is ongoing to develop drugs that modulate NNMT activity as potential treatments for diseases where NNMT is implicated.
NNMT has been linked to several diseases and health conditions, making it a potential target for therapeutic interventions.
NNMT dysregulation has been associated with metabolic disorders, cancer, neurodegenerative diseases, and cardiovascular diseases.
Customer Reviews (3)
Write a reviewIts high specificity and functional integrity ensure accurate and reproducible data, allowing researchers to draw meaningful conclusions from their experiments.
This protein is known for its exceptional quality and purity, providing reliable and consistent results.
The NNMT protein offers numerous advantages in trials and research experiments, making it an excellent choice for researchers.
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