Recombinant Human Thrombopoietin
Cat.No. : | THPO-176H |
- Specification
- Gene Information
- Related Products
Cat. No. : | THPO-176H |
Description : | Thrombopoietin (leukemia virus oncogene ligand, megakaryocyte growth and development factor), also known as THPO is a lineage-dominant hematopoietic cytokine. TPO is a glycoprotein hormone constitutively produced mainly by the liver and kidney and is the primary physiological regulator megakaryopoiesis and platelet production. |
Source : | Mammalian cells |
Molecular Weight : | The predicted molecular weight of Recombinant Human TPO is Mr 35 kDa. However, the actual molecular weight as observed by migration on SDS Page is Mr 80-90 kDa. |
State Of Matter : | Lyophilized. |
Biological Activity : | The biological activity of Human Thrombopoietin is determined by the dose-dependent stimulation of the proliferation of human MO7e cells. The expected ED50 for this effect is 1.0-3.0 ng/ml. |
Purity : | >90% by SDS Page and analyzed by silver stain. |
Endotoxin : | <1.0 EU/µg as determined by the LAL method. |
Storage And Stability : | This lyophilized protein is stable for six to twelve months when stored desiccated at -20°C to -70°C. After aseptic reconstitution, this protein may be stored at 2°C to 8°C for one month or at -20°C to -70°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles. See Product Insert for exact lot specific storage instructions. |
Gene Name : | THPO thrombopoietin [ Homo sapiens ] |
Synonyms : | thrombopoietin nirs variant 1; megakaryocyte stimulating factor; MKCSF; c-mpl ligand; megakaryocyte colony-stimulating factor; MGDF; megakaryocyte growth and development factor; MPL ligand; myeloproliferative leukemia virus oncogene ligand; C-mpl ligand; Megakaryocyte colony-stimulating factor; Megakaryocyte growth and development factor; MGC163194; Myeloproliferative leukemia virus oncogene ligand; Thrombopoietin; ML; TPO; MPLLG; THPO |
Gene ID : | 7066 |
mRNA Refseq : | NM_000460 |
Protein Refseq : | NP_000451 |
MIM : | 600044 |
UniProt ID : | P40225 |
Chromosome Location : | 3q27 |
Pathway : | Hematopoietic cell lineage |
Function : | cytokine activity; growth factor activity; hormone activity |
Products Types
◆ Recombinant Protein | ||
Thpo-6418M | Active Recombinant Mouse Thpo Protein | +Inquiry |
THPO-4490H | Recombinant Human THPO Protein, His (Fc)-Avi-tagged | +Inquiry |
THPO-2753H | Recombinant Human THPO protein(22-353 aa), N-SUMO & C-His-tagged | +Inquiry |
Thpo-111M | Recombinant Mouse Thpo Protein, His (Fc)-Avi-tagged | +Inquiry |
THPO-2755H | Recombinant Human THPO protein(22-353 aa), N-SUMO & N-His-tagged | +Inquiry |
◆ Lysates | ||
THPO-2273CCL | Recombinant Cynomolgus THPO cell lysate | +Inquiry |
THPO-001HCL | Recombinant Human THPO cell lysate | +Inquiry |
THPO-2831MCL | Recombinant Mouse THPO cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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