Recombinant Human PDCD4

• Cat.No.: PDCD4-30797TH
• Product Overview: Recombinant full length Human PDCD4 with proprietary tag; 77.7 kDa inclusive of tag. AAH31049

Specification

• Description: This gene is a tumor suppressor and encodes a protein that binds to the eukaryotic translation initiation factor 4A1 and inhibits its function by preventing RNA binding. Alternative splicing results in multiple transcript variants.
• Protein length: 470 amino acids
• Molecular Weight: 77.700kDa inclusive of tags
• Source: Wheat germ
• Tissue specificity: Up-regulated in proliferative cells. Highly expressed in epithelial cells of the mammary gland. Reduced expression in lung cancer and colon carcinoma.
• Biological activity: This product is useful for Antibody Production and Protein Array
• Form: Liquid
• Purity: Proprietary Purification
• Storage buffer: pH: 8.00Constituents:0.79% Tris HCl, 0.31% GlutathioneNote: Glutathione is reduced.
• Storage: Shipped on dry ice. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles.
• Sequence Similarities: Belongs to the PDCD4 family.Contains 2 MI domains.

Gene Information

• Gene Name: PDCD4 programmed cell death 4 (neoplastic transformation inhibitor) [ Homo sapiens ]
• Official Symbol: PDCD4
• Synonyms: PDCD4; programmed cell death 4 (neoplastic transformation inhibitor); programmed cell death protein 4; H731; nuclear antigen H731
• Gene ID: 27250
• mRNA Refseq: NM_001199492
• Protein Refseq: NP_001186421
• MIM: 608610
• Uniprot ID: Q53EL6
• Chromosome Location: 10q24
• Pathway: mTOR signaling pathway, organism-specific biosystem
• Function: RNA binding; binding; protein binding