Recombinant Mouse Growth Arrest Specific 6, His-tagged
Cat.No. : | Gas6-1741M |
Product Overview : | The DNA sequence encoding the signal peptide from CD33 (Met 1 - Ala 16), fused to the carboxy-terminal 6X his-tagged mature mouse Gas6 (Asp 115 - Pro 673) lacking the Gla domain was expressed inNSO cells. |
- Specification
- Gene Information
- Related Products
Cat. No. : | Gas6-1741M |
Description : | Growth arrest-specific 6, also known as GAS6 is a growth factor that serves as a ligand for members of the Axl subfamily of receptor protein-tyrosine kinases. GAS6 is expressed in hematopoietic tissue. GAS6 function as a direct regulator of osteoclastic function; they give an insight into the role of these vitamin K-dependent ligands in bone resorption in vivo. GAS6 has a potential therapeutic target to minimize graft-versus-host disease (GVHD). |
Molecular Weight : | The predicted molecular weight of Recombinant Mouse Gas6 is Mr 62 kDa. However, the actual molecular weight as observed by migration on SDS Page is Mr 72 kDa. |
Source : | Mammalian cells |
State Of Matter : | Lyophilized. |
Purity : | >95% by SDS Page and analyzed by silver stain. |
Endotoxin : | <1.0 EU/µg as determined by the LAL method. |
Biological Activity : | The biological activity of Mouse Gas6 was determined by its ability to bind rmAxl/Fc in a functional ELISA. Immobilized rmAxl/Fc at 2 μg/ml (100 μl/well) can bind rmGas6 with a linear range of 0.08 - 5 ng/ml. |
Storage And Stability : | This lyophilized protein is stable for six to twelve months when stored desiccated at -20°Cto -70°C. After aseptic reconstitution, this protein may be stored at 2°Cto 8°Cfor one month or at -20°Cto -70°Cin a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles. See Product Insert for exact lot specific storage instructions. |
Gene Name : | Gas6 growth arrest specific 6 [ Mus musculus ] |
Synonyms : | Gas6; growth arrest specific 6; Gas-6; GAS 6; growth arrest-specific |
Gene ID : | 14456 |
mRNA Refseq : | NM_019521 |
Protein Refseq : | NP_062394 |
UniProt ID : | Q61592 |
Chromosome Location : | 8 A1.1; 8 5.0 cM |
Function : | calcium ion binding; metal ion binding |
Products Types
◆ Recombinant Protein | ||
Gas6-1563R | Recombinant Rat Gas6 Protein, His&GST-tagged | +Inquiry |
GAS6-3014H | Recombinant Human GAS6 Protein, His (Fc)-Avi-tagged | +Inquiry |
GAS6-546H | Active Recombinant Human GAS6 Protein(Leu136~Phe311), His-tagged | +Inquiry |
GAS6-898M | Recombinant Mouse GAS6 Protein (Met1-Pro674), His-tagged | +Inquiry |
Gas6-3478M | Recombinant Mouse Gas6 Protein, His (Fc)-Avi-tagged | +Inquiry |
◆ Lysates | ||
GAS6-6017HCL | Recombinant Human GAS6 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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