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Native Human SHBG protein

Cat.No.: SHBG-30637TH
Product Overview: Native Human SHBG was purified from Human Serum.
Description: This gene encodes a steroid binding protein that was first described as a plasma protein secreted by the liver but is now thought to participate in the regulation of steroid responses. The encoded protein transports androgens and estrogens in the blood, binding each steroid molecule as a dimer formed from identical or nearly identical monomers. Polymorphisms in this gene have been associated with polycystic ovary syndrome and type 2 diabetes mellitus. Alternative splicing results in multiple transcript variants.
Source: Human Serum
Species: Human
Form: Lyophilized from 0.02 M ammonium bicarbonate.
Molecular Mass: ~45,000
Purity: > 90% (SDS-PAGE)
Storage: Store at -20 centigrade
Reconstitution: Use phosphate buffer pH > 7.0, containing 0.15M NaCl
Gene Name: SHBG sex hormone-binding globulin [ Homo sapiens ]
Official Symbol: SHBG
Synonyms: SHBG; sex hormone-binding globulin; ABP; androgen binding protein; MGC126834; MGC138391; TEBG; sex steroid-binding protein; testosterone-binding beta-globulin; testosterone-estrogen-binding globulin; testosterone-estradiol-binding globulin; testis-specific androgen-binding protein; SBP;
Gene ID: 6462
mRNA Refseq: NM_001040
Protein Refseq: NP_001031
MIM: 182205
UniProt ID: P04278

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Optional requirements on this protein    +Expand
C-fusion    N-fusion   Non-tagged
His    GST   Fc   Others
<1.0 eu/μg    <0.1 eu/μg   <0.01 eu/μg   Not required
Monomer Isolation    Dimer Isolation    Not required
>80% by SDS-PAGE    >90% by SDS-PAGE   >95% by SDS-PAGE   Others

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