Recombinant Human Poly (ADP-ribose) Polymerase 3, GST-tagged

• Cat.No.: PARP3-434H
• Product Overview: Recombinant Human PARP3, full length with N-terminal GST tag expressed in aBaculovirusinfected Sf9 cell expression system. MW = 87kDa.

Specification

• Cat. No.: PARP3-434H
• Description: Poly (ADP-ribose) polymerase (PARP) is a protein involved in a number of cellular processes involving mainly DNA repair and programmed cell death.
• Source: Sf9 cell.
• Purity: >80%.
• Application: Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling.
• Formulated In: 25 mM Tris-HCl, pH 8.0, 100 mM NaCl, 0.05% Tween-20, 30% glycerol, and 3 mM DTT.
• Stability: >6 months at –80°C.

Gene Information

• Gene Name: PARP3 poly (ADP-ribose) polymerase family, member 3 [ Homo sapiens ]
• Synonyms: PARP3; poly (ADP-ribose) polymerase 3; ADP-ribosyltransferase (NAD+; poly (ADP-ribose) polymerase)-like 2; ADP-ribosyltransferase (NAD+; poly (ADP-ribose) polymerase)-like 3; NAD+ ADP-ribosyltransferase 3; poly(ADP-ribose) synthetase-3; IRT1; ADPRT3; ADPRTL2; ADPRTL3; PADPRT-3; EC 2.4.2.30
• Gene ID: 10039
• mRNA Refseq: NM_001003931
• Protein Refseq: NP_001003931
• MIM: 607726
• UniProt ID: Q9Y6F1
• Chromosome Location: 3p21.31-p21.1
• Pathway: Base excision repair
• Function: NAD+ ADP-ribosyltransferase activity; identical protein binding; protein N-terminus binding; transcription factor binding; transferase activity, transferring glycosyl groups