Active Recombinant Human Left-right Determination Factor 1
Cat.No. : | Lefty1-1915H |
Product Overview : | Recombinant Human Left-right Determination Factor 1 was expressed inhuman 293 cells. |
- Specification
- Gene Information
- Related Products
Cat. No. : | LEFTY1-1915H |
Description : | Lefty (left-right determination factors) are proteins that are closely related members of the TGF-beta family of growth factors. These proteins are secreted and play a role in left-right asymmetry determination of organ systems during development. Mutations of the genes encoding these proteins have been associated with left-right axis malformations, particularly in the heart and lungs. |
Source : | Human 293 cells. |
Activity : | 10 to 40 ng/mL ED50. |
Purity : | >90%. |
Endotoxin : | Endotoxin-free. |
Molecular Mass : | 38 kDa, monomer, glycosylated. |
Purity Confirmation : | The protein was resolved by SDS polyacrylamide gel electrophoresis and the gel was stained with Coomassie blue. |
Activity Assay : | The specific activity was determined by dose dependent ability to inhibit BMP-4 (6.5 ng/mL) induction of alkaline phosphatase production in the MC-3T3-E1 cell line (Mouse chondrogenic cell line). |
Gene Name : | LEFTY1 left-right determination factor 1 [ Homo sapiens ] |
Synonyms : | LEFTB; LEFTYB; LEFTY1; left-right determination factor 1; left-right determination, factor B; Protein lefty-1; Left-right determination factor B; Protein lefty-B; UNQ278/PRO317 |
Gene ID : | 10637 |
mRNA Refseq : | NM_020997 |
Protein Refseq : | NP_066277 |
MIM : | 603037 |
UniProt ID : | O75610 |
Chromosome Location : | 1q42.1 |
Pathway : | TGF-beta signaling pathway |
Function : | cytokine activity; growth factor activity; transforming growth factor beta receptor binding |
Products Types
◆ Recombinant Protein | ||
LEFTY1-5033M | Recombinant Mouse LEFTY1 Protein, His (Fc)-Avi-tagged | +Inquiry |
LEFTY1-367H | Recombinant Human LEFTY1 Protein, His-tagged | +Inquiry |
LEFTY1-003H | Recombinant Human LEFTY1 Protein, Fc-tagged | +Inquiry |
Lefty1-370M | Recombinant Mouse Lefty1 Protein, His/GST-tagged | +Inquiry |
Lefty1-371R | Recombinant Rat Lefty1 Protein, His/GST-tagged | +Inquiry |
◆ Lysates | ||
LEFTY1-980HCL | Recombinant Human LEFTY1 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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