Recombinant Human SEMA5A protein, His-tagged
Cat.No. : | SEMA5A-3240H |
Product Overview : | Recombinant Human SEMA5A protein(NP_003957.2)(Met1-Met968), fused with His tag, was expressed in HEK293. |
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Source : | HEK293 |
Species : | Human |
Tag : | His |
Form : | Lyophilized from sterile PBS, pH 7.4Please contact us for any concerns or special requirements. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization. |
Molecular Mass : | The recombinant human SEMA5A consists of 957 amino acids and predictes a molecular mass of 107 kDa. In SDS-PAGE under reducing conditions, the apparent molecular mass of rh SEMA5A is approximately 130-140 kDa due to glycosylation. |
Protein Length : | Met1-Met968 |
Endotoxin : | < 1.0 EU per μg of the protein as determined by the LAL method |
Purity : | > 90 % as determined by SDS-PAGE |
Storage : | Samples are stable for up to twelve months from date of receipt at -20°C to -80°C Store it under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. |
Reconstitution : | It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4°C before opening to recover the entire contents. |
Gene Name : | SEMA5A sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A [ Homo sapiens ] |
Official Symbol : | SEMA5A |
Synonyms : | SEMA5A; sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A; SEMAF; semaphorin-5A; semF; sema F; semaphorin F; semaphorin-F; FLJ12815; |
Gene ID : | 9037 |
mRNA Refseq : | NM_003966 |
Protein Refseq : | NP_003957 |
MIM : | 609297 |
UniProt ID : | Q13591 |
Products Types
◆ Recombinant Protein | ||
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Sema5a-5762M | Recombinant Mouse Sema5a Protein, Myc/DDK-tagged | +Inquiry |
SEMA5A-4973R | Recombinant Rat SEMA5A Protein, His (Fc)-Avi-tagged | +Inquiry |
SEMA5A-603H | Recombinant Human SEMA5A Protein, MYC/DDK-tagged | +Inquiry |
SEMA5A-1969H | Recombinant Human SEMA5A Protein, His (Fc)-Avi-tagged | +Inquiry |
◆ Lysates | ||
SEMA5A-1310MCL | Recombinant Mouse SEMA5A cell lysate | +Inquiry |
SEMA5A-1860HCL | Recombinant Human SEMA5A cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (7)
Ask a questionSemaphorin-5A (SEMA5A) functions in cellular processes, primarily playing a role in neural development and axon guidance.
SEMA5A is predominantly localized in growth cones and axonal pathways within the nervous system.
There are potential therapeutic implications related to SEMA5A in neurological disorders involving neural development, making it a target for drug development.
SEMA5A participates in axon guidance and neuronal migration during neural development by interacting with Plexin-A and Neuropilin-1 receptors.
Specific receptors or co-receptors that SEMA5A interacts with include Plexin-A and Neuropilin-1, influencing its role in neural circuit formation.
SEMA5A contributes to the regulation of synaptic connectivity and plasticity in the nervous system, impacting neural circuit formation.
Dysregulation or abnormal expression of SEMA5A is associated with conditions such as autism spectrum disorders and developmental disorders.
Customer Reviews (3)
Write a reviewThe product's consistent outcomes fortified the reproducibility of our scientific inquiries.
Despite its cost, the product's contributions to our research goals made it an invaluable asset.
We appreciated the product's efficiency in achieving target protein upregulation with minimal time investment.
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