Recombinant Human TNFRSF11B, Fc Chimera

• Cat.No.: TNFRSF11B-19H
• Product Overview: Recombinant Human TNFRSF11B was produced inmammalian cells.It has a Fc Chimera at C-terminus fused with human IgG1F l.

Specification

• Cat. No.: TNFRSF11B-19H
• Description: Osteoclastogenesis inhibitory factor (C-terminus fused with human IgG1Fc) contains 402 amino acids with predicted MW 45.42 kDa x 2 (dimmer), and 24 cysteines. It also has 4 N-link glycosylation sites with MW increase up to 20kDa. OCIF (osteoclastogenesis inhibitory factor) or OPG inhibits osteoclastogenesis. Its ligand is osteoclast differentiation factor (ODF) or OPG ligand (OPGL).
• Source: Mammalian cells.
• Purity: >90%.
• Quantity: 2.0mg/2ml PBS.
• Recommended Storage TemPerature: -70℃.

Gene Information

• Gene Name: TNFRSF11B tumor necrosis factor receptor superfamily, member 11b [ Homo sapiens ]
• Synonyms: TNFRSF11B; tumor necrosis factor receptor superfamily, member 11b; OPG; TR1; OCIF; MGC29565; TNFRSF11B; osteoclastogenesis inhibitory factor
• Gene ID: 4982
• mRNA Refseq: NM_002546
• Protein Refseq: NP_002537
• MIM: 602643
• UniProt ID: O00300
• Chromosome Location: 8q24
• Pathway: Cytokine-cytokine receptor interaction
• Function: cytokine activity; protein binding; receptor activity