Factor Xa Inhibitor Screening Kit (Fluorometric)
Cat.No. : | Kit-2346 |
Product Overview : | Factor Xa (FXa) is the activated form of the coagulation factor X (Stuart-Power factor, thrombokinase, prothrombinase, thromboplastin, E.C.3.4.21.6). Factor X, a serine endopeptidase, plays an important role at several stages of the coagulation pathway. It acts by converting prothrombin into active thrombin by complexing with activated co-factor V in the prothrombinase complex. Unfractionated heparin and various low molecular weight heparins bind to plasma cofactor Antithrombin to inactivate several coagulation factors including factor Xa. Factor Xa inhibitor screening kit utilizes the ability of Factor Xa to cleave a synthetic substrate thereby releasing a fluorophore, AMC, which can be quantified by a fluorescence reader. In the presence of an inhibitor, the extent of the cleavage reaction is reduced or completely abolished. The loss in the fluorescence intensity can be correlated to the amount of inhibitor present in the assay solution. The Factor Xa Inhibitor Screening Kit is a simple, straightforward, high-throughput assay to screen Factor Xa inhibitors. |
- Specification
- Gene Information
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Applications : | Screening potential inhibitors of Factor Xa Characterizing/studying Factor Xa inhibitors in plasma samples |
Storage : | -20°C |
Size : | 100 assays |
Products Types
◆ Assay kits | ||
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Kit-0333 | F10 (Human) Chromogenic Activity Assay Kit | +Inquiry |
Kit-1050 | Factor XIa Activity Assay Kit (Colorimetric) | +Inquiry |
Kit-1062 | Factor XIIIa Activity Assay Kit (Colorimetric) | +Inquiry |
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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