HDAC6 Fluorogenic Assay Kit
Cat.No. : | Kit-1742 |
Product Overview : | HDACs regulate cellular processes by catalyzing the hydrolysis of an acetyl group from acetyllysines in modified proteins. In the HDAC assay, fluorescent-dye molecules are attached to a peptide containing acetyllysine. Attachment to the peptide quenches the fluorescence of the dye. After treatment of the peptide with an HDAC, the reaction is mixed with a development solution that is specific for nonacetylated lysines. If the acetyl group has been removed from the lysine by the HDAC, this solution will release the dye allowing for fluorescence. Fluorescence is therefore directly related to HDAC activity. |
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Size : | 96 reactions |
Applications : | Great for studying enzyme kinetics and screening small molecular inhibitors of HDAC6 for drug discovery and HTS applications. |
Storage : | 12 months from date of receipt, when stored as directed. Kit components require different storage conditions. Be sure to store each component at the proper temperature upon arrival. |
Products Types
◆ Recombinant Protein | ||
HDAC6-1877R | Recombinant Rhesus Macaque HDAC6 Protein, His (Fc)-Avi-tagged | +Inquiry |
HDAC6-313H | Active Recombinant Human HDAC6 Protein | +Inquiry |
HDAC6-096H | Recombinant Human HDAC6 Protein, GST-tagged | +Inquiry |
HDAC6-4092M | Recombinant Mouse HDAC6 Protein, His (Fc)-Avi-tagged | +Inquiry |
Hdac6-1104M | Recombinant Mouse Hdac6 Protein, MYC/DDK-tagged | +Inquiry |
◆ Lysates | ||
HDAC6-5603HCL | Recombinant Human HDAC6 293 Cell Lysate | +Inquiry |
◆ Assay kits | ||
Kit-1028 | HDAC6 Activity Assay Kit (Fluorometric) | +Inquiry |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (5)
Ask a questionYes, HDAC6 inhibitors can be combined with other therapies for enhanced efficacy. Synergistic effects may include improved anti-cancer activity or neuroprotection.
Yes, there are clinical trials exploring HDAC6 inhibitors as potential treatments. Positive outcomes could lead to new therapeutic options for patients.
HDAC6 is implicated in neurodegenerative diseases and inflammatory disorders. Understanding its role could lead to novel therapeutic approaches for these conditions.
HDAC6 regulates cell motility, protein trafficking, and other processes. Understanding these mechanisms is crucial for developing targeted therapies in various diseases.
Genetic variations in HDAC6 may influence individual responses to treatments. Personalized medicine approaches could consider these variations for better outcomes.
Customer Reviews (3)
Write a reviewTheir expertise and guidance have helped overcome hurdles, ensuring the smooth progress of my research.
The bands of proteins in Western Blotting experiments were very clear.
Its purity and consistency have provided me with reliable and reproducible results, ensuring the accuracy of my research findings.
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