Human Anti-Granulocyte Macrophage Colony Stimulating Factor Serum Reference standard

• Cat.No.: AGMCSF-162H
• Product Overview: This material is intended for use as an internal control in assays for detection of neutralizing antibodies to human GM-CSF in serum/plasma.

Specification

• Species: Human
• Usage: No attempt should be made to weigh out any portion of the freeze-dried material prior to reconstitution Reconstitute the vial with 0.5 ml of sterile distilled water. After reconstitution, the solution should be treated as a 1 in 4 dilution of le plasma.
• Notes: This preparation is not for administration to humans. The preparation contains material of human origin, and either the final product or the source materials, from which it is derived, have been tested and found negative for HBsAg, anti-HIV and HCV RNA. As with all materials of biological origin, this preparation should be regarded as potentially hazardous to health. It should be used and discarded according to your own laboratorys safety procedures. Such safety procedures should include the wearing of protective gloves and avoiding the generation of aerosols. Care should be exercised in opening ampoules or vials, to avoid cuts.
• Stability: Reference materials are held at Creative Biomart within assured, temperature- controlled storage facilities. Reference Materials should be stored on receipt as indicated on the label.
• Storage: Dilutions should be made in a protein-containing medium. Vials should be stored at -20°C and when reconstituted in aliquots at -40°C or below. The vials do not contain bacteriostat and solutions of the preparation should not be assumed to be sterile. Please note: because of the inherent stability of lyophilized material, Creative Biomart may ship these materials at ambient temperature.

Reviews

08/30/2020

 The protein product’s cost-effectiveness and clear instructions streamlined our experimental setup.

01/16/2020

 The return on investment from the protein product was significant due to the knowledge gained.

10/03/2017

 The unique characteristics of the product elevated our research to innovative heights.

09/19/2016

 Dependable outcomes reinforced the pivotal role of the product in our experimental outcomes.

03/25/2016

The product’s high purity enabled precise quantification, ensuring data accuracy.

Q&As

How is AGMCSF's role in the lung studied?

AGMCSF's role in lung homeostasis and inflammation is studied in respiratory diseases.

How is AGMCSF's signaling pathway studied?

Research explores AGMCSF's signaling via its receptor, leading to immune cell responses.

How is AGMCSF's involvement in inflammation studied?

AGMCSF's role in immune cell recruitment and activation contributes to inflammation studies.

How does AGMCSF impact wound healing?

AGMCSF's role in promoting macrophage activity contributes to wound healing.

How does AGMCSF impact dendritic cell function?

AGMCSF influences dendritic cell maturation and antigen presentation.

What's the role of AGMCSF in immune responses?

AGMCSF stimulates the production and differentiation of granulocytes and macrophages.

Can AGMCSF affect tissue-specific macrophage populations?

Yes, AGMCSF plays a role in differentiating tissue-specific macrophage subsets.

How does AGMCSF contribute to myeloid cell survival?

AGMCSF's role includes promoting survival and differentiation of myeloid cells.

Can AGMCSF affect monocyte differentiation?

Yes, AGMCSF promotes the differentiation of monocytes into macrophages.

Can AGMCSF be targeted for therapeutic interventions?

AGMCSF is considered for immunomodulatory therapies in certain conditions.

How does AGMCSF impact granulocyte survival?

AGMCSF contributes to granulocyte survival, helping maintain immune function.

How is AGMCSF's activity modulated?

AGMCSF activity can be modulated by receptor binding, cytokine interactions, and signaling.

How does AGMCSF influence hematopoiesis?

AGMCSF supports hematopoiesis by promoting the development of myeloid progenitor cells.

Does AGMCSF influence adaptive immune responses?

Yes, AGMCSF affects adaptive immune responses through its impact on antigen-presenting cells.

Can AGMCSF's signaling influence macrophage polarization?

Yes, AGMCSF signaling can influence macrophage polarization toward different functional states.

What is the AGMCSF protein?

AGMCSF stands for "Granulocyte-Macrophage Colony-Stimulating Factor," a cytokine that regulates immune cell production.

Can AGMCSF's activity affect allergic responses?

Yes, AGMCSF's role in immune cell activation is relevant in allergic responses.

Is AGMCSF involved in the cytokine storm?

Yes, AGMCSF's dysregulation can contribute to cytokine storms in severe inflammation.

Where is AGMCSF produced?

AGMCSF is produced by various cell types, including immune cells and stromal cells.

Can AGMCSF's activity influence immune cell function?

Yes, AGMCSF affects the function of granulocytes, macrophages, and dendritic cells.