Human Leucine-rich Alpha-2-glycoprotein 1

• Cat.No.: AHSG-1001H
• Product Overview: The Human Fetuin is purified from the human plasma.

Specification

• Description: AHSG, a glycoprotein present in the serum, is synthesized by hepatocytes. The AHSG molecule consists of two polypeptide chains, which are both cleaved from a proprotein encoded from a single mRNA. It is involved in several functions, such as endocytosis, brain development and the formation of bone tissue. The protein is commonly present in the cortical plate of the immature cerebral cortex and bone marrow hemopoietic matrix, and it has therefore been postulated that it participates in the development of the tissues. However, its exact significance is still obscure.
• Source: human plasma
• Species: Human
• Form: Filtered (0, 4 μm) and lyophilized in 0.5 mg/mL in PBS pH7.4
• Purity: >95%
• Applications: ELISA; Western blotting
• Quality Control Test: BCA to determine quantity of the protein; SDS PAGE to determine purity of the protein.
• Storage: Store lyophilized protein at -20°C . Lyophilized protein remains stable until the expiry date when stored at -20°C . Aliquot reconstituted protein to avoid repeated freezing/thawing cycles and store at -80°C for long term storage. Reconstituted protein can be stored at 4°C for a limited period of time; it does not show any change after two weeks at 4°C .
• Reconstitution: Add deionized water to prepare a working stock solution of approximately 0.5 mg/mL and let the lyophilized pellet dissolve completely. Product is not sterile! Please filter the product by an appropriate sterile filter before using it in the cell culture.

Gene Information

• Gene Name: AHSG alpha-2-HS-glycoprotein [ Homo sapiens ]
• Official Symbol: AHSG
• Synonyms: AHSG; alpha-2-HS-glycoprotein; A2HS; FETUA; HSGA; fetuin-A; alpha-2-Z-globulin; ba-alpha-2-glycoprotein; AHS
• Gene ID: 197
• mRNA Refseq: NM_001622
• Protein Refseq: NP_001613
• MIM: 138680
• UniProt ID: P02765
• Chromosome Location: 3q27.3
• Pathway: BMP receptor signaling, organism-specific biosystem
• Function: cysteine-type endopeptidase inhibitor activity; kinase inhibitor activity; receptor signaling protein tyrosine kinase inhibitor activity