Kappa Antibody-coupled magnetic MicroBeads
| Cat.No. : | Kappa-4592M |
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| Species : | Rat |
| Capacity : | for 1×10^9 total cells |
| Background : | A majority (95%) of all rat B cells express the Igκ light chain. Anti-Rat Kappa MicroBeads bind equally well to the Ig light chain allotypes Igκ-1a and Igκ-1b. Together with the Ig heavy chain, the Ig light chain is expressed on the surface of immature IgM+IgD- B cells. Furthermore, it is present on mature IgM+IgD+ B cells and memory B cells, and is down-regulated on activated B cells upon terminal differentiation into plasma cells. |
| Application : | B cells isolated with Anti-Rat Kappa MicroBeads from peripheral lymphoid organs or non-hematopoietic tissues are suitable for in vivo and in vitro studies on B cell development, differentiation, and migration. Highly pure B cell populations are also required for reliable cellular and molecular analyses, for example, of Ig gene rearrangement. |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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