α-L-Fucosidase Assay Kit

• Cat.No.: Kit-2074
• Product Overview: The non-radioactive, colorimetric AFU assay is based on the cleavage of 4-nitrophenol from the synthetic substrate. Nitrophenolbecomes intensely colored after addition of the stop reagent. The increase in absorbance at 405 nm after addition of the stop reagent is directly proportional to the enzyme activity.

Specification

• Size: 100 tests
• Applications: For quantitative determination of α-L-Fucosidase activity in biological samples (e.g. plasma, serum, tissue, cell lysate, etc.)
• Storage: The kit is shipped at room temperature. Store all components at 4°C upon receiving. Shelf life: 6 months after receipt.

Reviews

09/08/2021

Investigating protein-protein interactions in cellular senescence for aging-related diseases.

06/26/2020

Mapping protein-protein interactions in immune checkpoint regulation for immunotherapy.

03/15/2020

Unraveling protein-protein interactions in RNA splicing for gene expression regulation.

Q&As

What is the impact of AFU protein knockdown or overexpression on cellular phenotypes?

Modulating AFU protein expression levels can affect cellular phenotypes, such as proliferation, apoptosis, or differentiation.

Does AFU protein have a role in cellular migration or invasion?

AFU protein may contribute to cellular migration or invasion processes, potentially impacting tissue remodeling or tumor metastasis.

What are the functional domains or motifs of AFU protein?

AFU protein contains specific domains or motifs that contribute to its functional properties, such as DNA-binding or protein-protein interaction domains.

Are there disease-associated genetic variations in the AFU gene?

Some genetic variations in the AFU gene have been associated with certain diseases or susceptibility to specific conditions.

What is the tissue-specific expression pattern of AFU protein?

AFU protein exhibits tissue-specific expression, with higher levels observed in certain organs or cell types.

How does AFU protein regulate gene expression?

AFU protein can interact with transcription factors or chromatin modifiers to modulate gene expression.

Does AFU protein interact with specific cellular signaling pathways?

AFU protein can interact with signaling pathways involved in cell proliferation, survival, or differentiation.

What is the role of AFU protein in cellular metabolism?

AFU protein may participate in the regulation of cellular metabolism, including nutrient uptake or energy production.

What are the potential therapeutic implications of targeting AFU protein?

Targeting AFU protein may hold therapeutic potential for certain diseases, but further research is needed to explore its precise therapeutic applications.

Does AFU protein undergo post-translational modifications?

Yes, AFU protein can undergo post-translational modifications such as phosphorylation, acetylation, or ubiquitination.