Native Human F2R Protein
Cat.No. : | F2R-27H |
Product Overview : | Native human F2R protein without tag was isolated from human blood. |
- Specification
- Gene Information
- Related Products
Description : | Thrombin is the last enzyme in the clotting cascade functioning to cleave fibrinogen to fibrin and potentiates the procoagulation process by activating factors V, VIII, XI, and XIII. Conversely, thrombin aids the anticoagulant process by activating protein C. Activated protein C inhibits activated factors V and VIII ultimately down-regulating further thrombin production. Thrombin is often used as a potent platelet activator in vitro. Platelet responses to thrombin are mediated through protease-activated receptors (PARs). Thrombin-mediated signaling regulates a diverse range of metabolic processes including activation of phospholipases in platelets, endothelial cells, and cardiac myocytes. |
Source : | Human Blood |
Species : | Human |
Molecular Mass : | 38 kDa |
Stability : | ≥ 1 year |
Storage : | Store it at -80 centigrade |
Storage Buffer : | 5 mM sodium citrate, pH 6.5, containing 0.01% PEG and 20 mM sodium chloride |
Gene Name : | F2R coagulation factor II thrombin receptor [ Homo sapiens (human) ] |
Official Symbol : | F2R |
Synonyms : | F2R; coagulation factor II thrombin receptor; TR; HTR; CF2R; PAR1; PAR-1; proteinase-activated receptor 1; protease-activated receptor 1 |
Gene ID : | 2149 |
mRNA Refseq : | NM_001311313 |
Protein Refseq : | NP_001298242 |
MIM : | 187930 |
UniProt ID : | P25116 |
Products Types
◆ Recombinant Protein | ||
F2R-2917M | Recombinant Mouse F2R Protein, His (Fc)-Avi-tagged | +Inquiry |
F2R-3613H | Recombinant Human F2R Protein, GST-tagged | +Inquiry |
F2r-2176R | Recombinant Rat F2r Protein, His-tagged | +Inquiry |
F2R-2891H | Recombinant Human F2R Protein, His (Fc)-Avi-tagged | +Inquiry |
F2R-367H | Recombinant Human F2R Protein, His-tagged | +Inquiry |
◆ Lysates | ||
F2R-2116HCL | Recombinant Human F2R cell lysate | +Inquiry |
◆ Assay kits | ||
Kit-1232 | F2R (PAR1) CHO-K1 β-Arrestin GPCR Assay Kit | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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