Native Human Transferring
Cat.No. : | TF-5341H |
Product Overview : | Native human TFexpressed by Human Plasma is a 76.5 kDa protein. |
- Specification
- Gene Information
- Related Products
Cat. No. : | TF-5341H |
Description : | Transferrin(TF) is a glycoprotein thought to have been created as a result of an ancient geneduplication event that led to generation of homologous C- and N-terminaldomainseachof which binds one ion of Ferric Iron. Therefore, each Human TF molecule hastheabilityto carry two Iron ions in the Ferric form (Fe3+). The function of TF is totransport Iron fromthe intestine, reticuloendothelial system, and liver parenchymal cells to all proliferatingcells in the body. TF may also have a physiologic role as Granulocyte/Pollen-BindingProtein (GPBP) involved in the removal of certain organic matterand allergens from serum. Apo-Transferrin designates the form of the molecule withoutIron bound. Like TF, APO-TF has a physiological role in the transportationanddistributionof Iron among the body organs. It is also an important transport factor used indefined culture media. |
Source : | Human Plasma |
Species : | Human |
Form : | Lyophilized fromAmmonium Bicarbonate pH 7.2. |
Molecular Weight : | 76.5 kDa |
Reconstitution : | Centrifugevial prior to opening. Add deionized water to a concentration of10 mg/Ml, aliquotand freeze unused portion. |
Purity : | > 95% by SDS-PAGE; Purifiedto have < 0.02 mgIron/g TF. |
Storage : | Store at -70°C. 3years from delivery. Avoid repeated freeze-thaw cycles. |
OfficialSymbol : | TF |
Gene Name : | TF transferrin [ Homo sapiens] |
Synonyms : | TF; transferring; TFQTL1;PRO1557; PRO2086; DKFZp781D0156; serotransferrin; siderophilin; OTTHUMP00000197155;beta-1 metal-binding globulin |
Gene ID : | 7018 |
mRNA Refseq : | NM_001063 |
Protein Refseq : | NP_001054 |
MIM : | 190000 |
UniProt ID : | P02787 |
Chromosome Location : | 3q22.1 |
Pathway : | EPHB forwardsignaling; HIF-1-alpha transcription factor network; Hemostasis; Iron uptakeand transport; Mineral absorption; Platelet activation; Plateletdegranulation; Response to elevated platelet cytosolic Ca2+; Transferrinendocytosis and recycling; Transmembrane transport of small molecules |
Function : | ferric iron binding;metal ion binding; protein binding; ubiquitin protein ligase binding |
Products Types
◆ Recombinant Protein | ||
Trf-148M | Recombinant Mouse Trf Protein, His-tagged | +Inquiry |
Tf-566R | Active Recombinant Rat Tf protein(Met1-Ser698), His-tagged | +Inquiry |
TF-2175H | Recombinant Human TF Protein, His (Fc)-Avi-tagged | +Inquiry |
TF-5682R | Recombinant Rat TF Protein, His (Fc)-Avi-tagged | +Inquiry |
TF-146B | Recombinant Bovine TF Protein, His-tagged | +Inquiry |
◆ Native Protein | ||
TF-261M | Native Monkey Transferrin | +Inquiry |
TF-136C | Native Chicken Ovotransferrin | +Inquiry |
Trf-70M | Native Mouse Apotransferrin | +Inquiry |
◆ Lysates | ||
TF-1554SCL | Recombinant Sus scrofa (Pig) TF cell lysate | +Inquiry |
TF-1208MCL | Recombinant Mouse TF cell lysate | +Inquiry |
TF-001RCL | Recombinant Rat TF cell lysate | +Inquiry |
◆ Assay kits | ||
Kit-0813 | TF (Human) Chromogenic Activity Assay Kit | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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