Native Mouse Coagulation Factor II
Cat.No. : | F2-5287M |
Product Overview : | Mouse F2 isprepared from fresh frozen mouse plasma. |
- Specification
- Gene Information
- Related Products
Cat. No. : | F2-5287M |
Description : | F2is proteolytically cleaved to form thrombin in the first step of thecoagulation cascade, which ultimately results in the stemming of blood loss.F2 in turn acts as a serine protease that converts soluble fibrinogen intoinsoluble strands of fibrin, as well as catalyzing many other coagulation-relatedreactions. |
Source : | Mouse plasma |
Form : | Frozenliquid in 0.05 M HEPES Buffer + 0.1 M NaCl, pH 7.4. |
Purity : | > 95% by SDS-PAGEanalysis. |
MolecularWeight : | 72 kDa |
EndotoxinLevel : | < 0.1ng/μg of protein |
Biological Activity : | Activityis measured by clotting and/or chromogenic substrate assay, following conversionof prothrombinto thrombin. |
Concentration : | 5.0mg/ml |
Storage : | Store at -80°C. Stable for 3 years from delivery. Avoid repeated freeze-thaw cycles. |
Pathways : | BloodClotting Cascade; Cell surface interactions at the vascular wall; ClassA/1(Rhodopsin-like receptors); Common Pathway; Complement and CoaqulationCascades; Diabetes pathways; FOXA2 and FOXA3 transcription factor networks; ExtrinsicPathway; Formation of Fibrin Clot (Clotting Cascade); Hemostasis; IntrinsicPathway; Regulation of actin cytoskeleton; Selenium Pathway; SignalTransduction |
Gene Name : | F2coagulation factor II [ Mus musculus ] |
Official Symbol : | F2 |
Synonyms : | F2; coagulation factor II;prothrombin; thrombin; Cf2; FII; Cf-2; OTTMUSP00000015068; EC 3.4.21.5;Prothrombin; Coagulation factor II; Thrombin light chain; Thrombin heavychain |
Gene ID : | 14061 |
mRNA Refseq : | NM_010168 |
Protein Refseq : | NP_034298 |
UniProt ID : | P19221 |
Chromosome Location : | 2 |
Function : | peptidaseactivity;serine-typeendopeptidase activity; calcium ion binding; receptor binding; thrombospondinreceptor activity; catalytic activity; hydrolase activity; serine-type peptidaseactivity |
Products Types
◆ Recombinant Protein | ||
F2-995M | Recombinant Mouse F2 Protein, MYC/DDK-tagged | +Inquiry |
F2-907P | Recombinant Pig F2 Protein, His-tagged | +Inquiry |
F2-1356R | Recombinant Rhesus Macaque F2 Protein, His (Fc)-Avi-tagged | +Inquiry |
F2-1186M | Active Recombinant Mouse F2 protein(Met1-Gly618), His-tagged | +Inquiry |
F2-1450R | Recombinant Rat F2 Protein, His-tagged | +Inquiry |
◆ Native Protein | ||
F2-5402P | Native Porcine Coagulation Factor II (thrombin) | +Inquiry |
F2-5401B | Native Bovine Coagulation Factor II (thrombin) | +Inquiry |
Thrombin-21H | Active Native Cattle Thrombin | +Inquiry |
◆ Lysates | ||
F2-2124MCL | Recombinant Mouse F2 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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