Recombinant Cattle IFNT2 Protein, His-tagged
Cat.No. : | IFNT2-985C |
Product Overview : | Recombinant Cattle IFNT2 Protein (Cys24-Leu195) with His tag was expressed in E. coli. |
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Description : | Paracrine hormone primarily responsible for maternal recognition of pregnancy. Interacts with endometrial receptors, probably type I interferon receptors, and blocks estrogen receptor expression, preventing the estrogen-induced increase in oxytocin receptor expression in the endometrium. This results in the suppression of the pulsatile endometrial release of the luteolytic hormone prostaglandin F2-alpha, hindering the regression of the corpus luteum (luteolysis) and therefore a return to ovarian cyclicity. This, and a possible direct effect of IFN-tau on prostaglandin synthesis, leads in turn to continued ovarian progesterone secretion, which stimulates the secretion by the endometrium of the nutrients required for the growth of the conceptus. In summary, displays particularly high antiviral and antiproliferative potency concurrently with particular weak cytotoxicity, high antiluteolytic activity and immunomodulatory properties. In contrast with other IFNs, IFN-tau is not virally inducible. |
Source : | E. coli |
Species : | Cattle |
Tag : | N-His |
Form : | Freeze-dried powder |
Molecular Mass : | Predicted Molecular Mass: 23.5 kDa; Accurate Molecular Mass: 23 kDa |
Protein length : | Cys24-Leu195 |
Purity : | > 97% |
Applications : | Positive Control; Immunogen; SDS-PAGE; WB. |
Stability : | The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 centigrade for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition. |
Storage : | Avoid repeated freeze/thaw cycles. Store at 2-8 centigrade for one month. Aliquot and store at -80 centigrade for 12 months. |
Storage Buffer : | 100mM NaHCO3, 500mM NaCl, pH8.3, containing 1mM EDTA, 1mM DTT, 0.01% SKL, 5% Trehalose and Proclin300. |
Reconstitution : | Reconstitute in ddH2O to a concentration of 0.1-1.0 mg/mL. Do not vortex. |
Gene Name : | IFNT2 interferon tau [ Bos taurus (cattle) ] |
Official Symbol : | IFNT2 |
Synonyms : | IFNT2; interferon tau; IFNT; TP-1; IFNT1; IFN-tau-c2; interferon tau-2; IFN-tau-1; IFN-tau-2; IFN-tau1; IFN-tau2; antiluteolysin; interferon alpha II; interferon tau-1; interferon, trophoblast; interferon-tau1e; interferon-tau3e; trophoblast antiluteolytic protein; trophoblast protein-1; trophoblast type I interferon; trophoblastin |
Gene ID : | 317698 |
mRNA Refseq : | NM_001015511 |
Protein Refseq : | NP_001015511 |
UniProt ID : | P15696 |
Products Types
◆ Recombinant Protein | ||
IFNT2-170B | Recombinant Bovine IFNT2 Protein, His-tagged | +Inquiry |
IFNT2-1583B | Recombinant Bovine IFNT2 Protein (24-195 aa), His-tagged | +Inquiry |
IFNT2-49B | Recombinant Bovine IFNT2 protein, His-tagged | +Inquiry |
IFNT2-11B | Active Recombinant Bovine IFNT2 | +Inquiry |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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