Recombinant Cynomolgus CLEC4E protein, Fc-tagged

• Cat.No.: CLEC4E-290C
• Product Overview: Recombinant Cynomolgus CLEC4E fused with the Fc region of human IgG1 at N-terminal was expressed in HEK293.

Specification

• Source: HEK293
• Species: Cynomolgus
• Tag: Fc
• Predicted N Terminal: Glu
• Form: Lyophilized from sterile PBS, pH 7.4.1. Normally 5 % - 8 % trehalose and mannitol are added as protectants before lyophilization. Specific concentrations are included in the hardcopy of COA.2. Please contact us for any concerns or special requirements.
• Molecular Mass: The recombinant cynomolgus CLEC4E consists 439 amino acids and predicts a molecular mass of 49.1 kDa.
• Endotoxin: < 1.0 EU per μg protein as determined by the LAL method.
• Purity: > 85 % as determined by SDS-PAGE.
• Stability: Samples are stable for up to twelve months from date of receipt at -70 centigrade
• Storage: Store it under sterile conditions at -20 centigrade to -80 centigrade. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
• Reconstitution: A hardcopy of COA with reconstitution instruction is sent along with the products. Please refer to it for detailed information.
• Shipping: In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature.Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.

Gene Information

• Gene Name: CLEC4E C-type lectin domain family 4, member E [ Macaca fascicularis ]
• Official Symbol: CLEC4E
• Synonyms: C-type lectin domain family 4, member E
• Gene ID: 102121864
• Chromosome Location: chromosome: 11
• Pathway: Tuberculosis, organism-specific biosystem; Tuberculosis, conserved biosystem

Reviews

10/24/2022

The CLEC4E protein is an exceptional protein solution that exceeds expectations in terms of quality and suitability for my experimental requirements.

01/01/2021

I am confident that utilizing the CLEC4E protein will empower me to uncover crucial insights into cellular mechanisms with precision.

03/11/2020

In addition to its outstanding quality, the CLEC4E protein comes with exceptional technical support from its manufacturer.

Q&As

Can CLEC4E protein be targeted for the treatment of autoimmune diseases?

While the role of CLEC4E in autoimmune diseases is still being investigated, targeting CLEC4E may hold potential for modulating immune responses in certain autoimmune conditions.

How does CLEC4E protein contribute to immune responses?

CLEC4E protein activates immune cells and initiates inflammatory responses upon recognition of pathogen-associated molecular patterns (PAMPs).

Is CLEC4E protein involved in antiviral immune responses?

Yes, CLEC4E is involved in recognizing viral pathogens and triggering immune responses to combat viral infections.

How does CLEC4E protein interact with other immune receptors?

CLEC4E can collaborate with other immune receptors, such as TLRs (Toll-like receptors), to amplify immune responses upon pathogen detection.

Are there any specific diseases where targeting CLEC4E shows promise?

Targeting CLEC4E holds promise in the development of vaccines and immunotherapies against infectious diseases, including tuberculosis and fungal infections.