Description : |
The protein encoded by this gene is part of the T-cell receptor/CD3 complex (TCR/CD3 complex) and is involved in T-cell development and signal transduction. The encoded membrane protein represents the delta subunit of the CD3 complex, and along with four other CD3 subunits, binds either TCR alpha/beta or TCR gamma/delta to form the TCR/CD3 complex on the surface of T-cells. Defects in this gene are a cause of severe combined immunodeficiency autosomal recessive T-cell-negative/B-cell-positive/NK-cell-positive (SCIDBNK). Two transcript variants encoding different isoforms have been found for this gene. Other variants may also exist, but the full-length natures of their transcripts has yet to be defined. |
Source : |
HEK293 |
Species : |
Cynomolgus monkey |
Tag : |
His |
Form : |
Lyophilized |
Molecular Mass : |
14.3 kDa |
Protein Length : |
171 |
AA Sequence : |
MEHSTFLSGLVLATLLSQVSPFKIP VEELEDRVFVKCNTSVTWVEGTVGT LLTNNTRLDLGKRILDPRGIYRCNG TDIYKDKESAVQVHYRMCQNCVELD PATLAGIIVTDVIATLLLALGVFCF AGHETGRLSGAADTQALLRNDQVYQ PLRDRDDAQYSRLGGNWARNK |
Purity : |
> 98% |
Applications : |
WB; ELISA; FACS; FC |
Stability : |
This bioreagent is stable at 4 centigrade (short-term) and -70 centigrade(long-term). After reconstitution, sample may be stored at 4 centigrade for 2-7 days and below -18 centigrade for future use. |
Storage : |
At -20 centigrade. |
Concentration : |
1 mg/mL |
Storage Buffer : |
PBS (pH 7.4-7.5). Sterile-filtered colorless solution. |
Reconstitution : |
Reconstitute in sterile distilled H2O to no less than 100 μg/mL; dilute reconstituted stock further in other aqueous solutions if needed. Please review COA for lot-specific instructions. Final measurements should be determined by the end-user for optimal performance. |