Recombinant Cynomolgus MSLN Protein, Asp296-Gly580, C-His tagged, Biotinylated
Cat.No. : | MSLN-006C |
Product Overview : | Recombinant Cynomolgus MSLN/Mesothelin-C-His protein was developed from HEK293 and has a target region of C-His. |
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Description : | This gene encodes a preproprotein that is proteolytically processed to generate two protein products, megakaryocyte potentiating factor and mesothelin. Megakaryocyte potentiating factor functions as a cytokine that can stimulate colony formation of bone marrow megakaryocytes. Mesothelin is a glycosylphosphatidylinositol-anchored cell-surface protein that may function as a cell adhesion protein. This protein is overexpressed in epithelial mesotheliomas, ovarian cancers and in specific squamous cell carcinomas. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed. |
Source : | HEK293 |
Species : | Cynomolgus |
Tag : | C-His |
Protein length : | Asp296-Gly580 |
Conjugation/Label : | Biotin |
Form : | Lyophilised |
Endotoxin : | Endotoxin level was found to be less than 0.1 ng/μg (1 EU/μg). |
Notes : | FOR RESEARCH USE ONLY (RUO). |
Storage : | The lyophilized protein is stable for at least 1 year from date of receipt at -20 centigrade. |
Storage Buffer : | Lyophilised from 0.2 μm filtered PBS solution pH 7.4. Upon receipt centrifuge vial to ensure maximal product extraction, recommended: 20 sec, 5K RPM |
Gene Name : | MSLN mesothelin [ Macaca mulatta (Rhesus monkey) ] |
Official Symbol : | MSLN |
Synonyms : | MSLN; mesothelin; |
Gene ID : | 698095 |
mRNA Refseq : | XM_028840606 |
Protein Refseq : | XP_028696439 |
UniProt ID : | G7NQF2 |
Products Types
◆ Recombinant Protein | ||
MSLN-8392H | Active Recombinant Human MSLN Protein | +Inquiry |
MSLN-318H | Recombinant Human MSLN Protein (Glu 296 - Gly 580), His-tagged, PE-Labeled | +Inquiry |
MSLN-381H | Recombinant Human MSLN Protein, His-tagged, Biotinylated | +Inquiry |
MSLN-09H | Recombinant Human MSLN Protein, C-6His-Avi tagged, Biotinylated | +Inquiry |
MSLN-3297H | Recombinant Human MSLN protein(Glu296-Gly580), His-tagged | +Inquiry |
◆ Lysates | ||
MSLN-1316HCL | Recombinant Human MSLN cell lysate | +Inquiry |
MSLN-1343HCL | Recombinant Human MSLN cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (7)
Ask a questionMSLN is normally expressed in mesothelial cells, playing a role in cell adhesion.
In cancer, MSLN expression is significantly upregulated.
MSLN is overexpressed in mesothelioma, ovarian, and pancreatic cancers.
Therapies targeting MSLN include antibody-drug conjugates and CAR-T cell therapies.
MSLN levels can be assessed through immunohistochemistry and serum biomarker tests.
MSLN overexpression is often associated with poor prognosis in cancer patients.
MSLN promotes tumor cell proliferation, invasion, and resistance to apoptosis.
Customer Reviews (3)
Write a reviewVery satisfied, great product.
Product is high-quality.
Excellent for experiments, reliable.
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