Recombinant Full Length Bovine Translocator Protein(Tspo) Protein, His-Tagged
Cat.No. : | RFL12138BF |
Product Overview : | Recombinant Full Length Bovine Translocator protein(TSPO) Protein (P30535) (1-169aa), fused to N-terminal His tag, was expressed in E. coli. |
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Source : | E.coli expression system |
Species : | Bos taurus (Bovine) |
Tag : | His |
Form : | Lyophilized powder |
Protein length : | Full Length (1-169) |
AA Sequence : | MAPPWVPAVGFTLLPSLGGFLGAQY TRGEGFRWYASLQKPPWHPPRWILA PIWGTLYSAM GYGSYMIWKELGGFSKEAVVPLGLY AGQLALNWAWPPLFFGTRQMGWALV DLLLTGGMAA ATAMAWHQVSPPAACLLYPYLAWLA FAGMLNYRMWQDNQVRRSGRRLSE |
Purity : | Greater than 90% as determined by SDS-PAGE. |
Applications : | SDS-PAGE |
Notes : | Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week. |
Storage : | Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles. |
Storage Buffer : | Tris/PBS-based buffer, 6% Trehalose, pH 8.0 |
Reconstitution : | We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference. |
Gene Name : | TSPO |
Synonyms : | TSPO; BZRP; Translocator protein; Isoquinoline-binding protein; IBP; PKBS; Peripheral-type benzodiazepine receptor; PBR |
UniProt ID : | P30535 |
Gene Name : | TSPO |
Synonyms : | TSPO; BZRP; Translocator protein; Isoquinoline-binding protein; IBP; PKBS; Peripheral-type benzodiazepine receptor; PBR |
UniProt ID : | P30535 |
Products Types
◆ Recombinant Protein | ||
Tspo-728M | Recombinant Mouse Tspo Protein, MYC/DDK-tagged | +Inquiry |
TSPO-4819R | Recombinant Rhesus Macaque TSPO Protein, His (Fc)-Avi-tagged | +Inquiry |
TSPO-5985R | Recombinant Rat TSPO Protein, His (Fc)-Avi-tagged | +Inquiry |
TSPO-9691M | Recombinant Mouse TSPO Protein, His (Fc)-Avi-tagged | +Inquiry |
TSPO-2267H | Recombinant Human TSPO Protein, His (Fc)-Avi-tagged | +Inquiry |
◆ Lysates | ||
TSPO-703HCL | Recombinant Human TSPO 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (6)
Ask a questionTSPO has an impact on neuroprotection by modulating mitochondrial function to affect the survival and death of nerve cells. Specific mechanisms include inhibition of apoptosis and alleviation of oxidative stress.
At present, the research on TSPO faces some challenges, such as the difference in the expression of TSPO in various tissues, the functional changes of TSPO in different disease states, and the interaction between TSPO and other molecules. However, with the continuous advancement of technology and the in-depth understanding of the functions of TSPO, it is expected that there will be greater breakthroughs in drug design and treatment strategies for TSPO in the future.
This protein regulates the permeability of mitochondrial membranes to cholesterol by binding to cholesterol transporters, thereby affecting cholesterol synthesis and trafficking.
Since TSPO is associated with a variety of diseases,it may be a therapeutic target for a variety of diseases, such as neurodegenerative diseases, cancer, and mental disorders. Some progress has been made in the design and development of drugs for TSPO.
Commonly used TSPO detection methods include immunohistochemistry, western blotting, flow cytometry, etc. In addition, TSPO ligands can also be used for binding experiments or functional experiments to study their biological functions.
The expression level of TSPO changes in a variety of physiological and pathological conditions, such as hypoxia, ischemia, inflammation, aging, etc. These changes affect the function of the mitochondria, which affects the survival and death of cells.
Customer Reviews (3)
Write a reviewProlonged transportation will not affect the stability of the product.
The price of this one is very reasonable, and the quality is very good, I am very satisfied.
It has high solubility and can be dissolved quickly.
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