Recombinant Full Length Chicken Type-1 Angiotensin Ii Receptor(Agtr1) Protein, His-Tagged
Cat.No. : | RFL-36544GF |
Product Overview : | Recombinant Full Length Chicken Type-1 angiotensin II receptor(AGTR1) Protein (P79785) (1-359aa), fused to N-terminal His tag, was expressed in E. coli. |
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Source : | E.coli expression system |
Species : | Gallus gallus (Chicken) |
Tag : | His |
Form : | Lyophilized powder |
Protein length : | Full Length (1-359) |
AA Sequence : | MVPNYSTEETVKRIHVDCPVSGRHS YIYIMVPTVYSIIFIIGIFGNSLVV IVIYCYMKLK TVASIFLLNLALADLCFLITLPLWA AYTAMEYQWPFGNCLCKLASAGISF NLYASVFLLT CLSIDRYLAIVHPVKSRIRRTMFVA RVTCIVIWLLAGVASLPVIIHRNIF FAENLNMTVC GFRYDNNNTTLRVGLGLSKNLLGFL IPFLIILTSYTLIWKTLKKAYQIQR NKTRNDDIFK MIVAIVFFFFFSWIPHQVFTFLDVL IQLHVITDCKITDIVDTAMPFTICI AYFNNCLNPF FYVFFGKNFKKYFLQLIKYIPPNVS THPSLTTKMSSLSYRPPENIRLPTK KTAGSFDAE |
Purity : | Greater than 90% as determined by SDS-PAGE. |
Applications : | SDS-PAGE |
Notes : | Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week. |
Storage : | Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles. |
Storage Buffer : | Tris/PBS-based buffer, 6% Trehalose, pH 8.0 |
Reconstitution : | We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference. |
Gene Name : | AGTR1 |
Synonyms : | AGTR1; Type-1 angiotensin II receptor; Angiotensin II type-1 receptor; AT1 |
UniProt ID : | P79785 |
Gene Name : | AGTR1 |
Synonyms : | AGTR1; Type-1 angiotensin II receptor; Angiotensin II type-1 receptor; AT1 |
UniProt ID : | P79785 |
Products Types
◆ Recombinant Protein | ||
AGTR1-1320H | Recombinant Human AGTR1 Protein (297-359 aa), His-tagged | +Inquiry |
AGTR1-97H | Recombinant Human AGTR1 Protein, His-tagged | +Inquiry |
AGTR1-1057HFL | Recombinant Human AGTR1 protein, His&Flag-tagged | +Inquiry |
AGTR1-29H | Recombinant Human AGTR1, GST-tagged | +Inquiry |
AGTR1-28H | Recombinant Human AGTR1 | +Inquiry |
◆ Lysates | ||
AGTR1-8970HCL | Recombinant Human AGTR1 293 Cell Lysate | +Inquiry |
◆ Assay kits | ||
Kit-2188 | AGTR1 CHO-K1 β-Arrestin GPCR Assay Kit | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (10)
Ask a questionAGTR1 activation in the kidneys leads to vasoconstriction of renal blood vessels, increased sodium reabsorption, and stimulation of aldosterone release, ultimately impacting renal function.
Overactivation of AGTR1 can lead to increased vasoconstriction, sodium retention, and stimulation of aldosterone release, all of which contribute to hypertension.
AGTR1 is widely expressed throughout the body, with high levels found in the cardiovascular system, kidneys, and adrenal glands.
Yes, genetic variations in the AGTR1 gene have been associated with increased susceptibility to cardiovascular diseases, hypertension, and other conditions influenced by the renin-angiotensin system.
AGTR1 activation can modulate inflammatory responses, contributing to inflammation-associated conditions such as atherosclerosis and chronic kidney disease.
Upon angiotensin II binding, AGTR1 activates intracellular signaling pathways, such as G-protein-mediated pathways and the activation of downstream kinases.
AGTR1 activation can promote angiogenesis, the formation of new blood vessels, by stimulating endothelial cell proliferation and migration.
AGTR1 can activate pathways such as the phosphoinositide 3-kinase (PI3K)/Akt pathway, mitogen-activated protein kinase (MAPK) pathway, and the Janus kinase/signal transducer and activator of transcription (JAK/STAT) pathway.
AGTR1 has been implicated in cancer development and progression due to its role in cellular growth, angiogenesis, and inflammation.
AGTR1 activation can promote the generation of reactive oxygen species, contributing to oxidative stress and cellular damage.
Customer Reviews (5)
Write a reviewIt's like a ray of sunshine in our experiments, bringing joy and reliable data. A true delight to work with!
I have been a loyal customer of this supplier for years due to their commitment to delivering proteins of exceptional quality at competitive prices.
The post-sale services provided detailed technical support and ensured that I had a positive experience with their products.
Love the affordable price and great quality of the recombinant proteins I purchased!
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