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Recombinant Full Length Human ABHD1 Protein, GST-tagged

Cat.No. : ABHD1-823HF
Product Overview : Human ABHD1 full-length ORF ( AAH39576, 1 a.a. - 405 a.a.) recombinant protein with GST-tag at N-terminal.
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Description : This gene is a member of the AB hydrolase superfamily and encodes a protein with an alpha/beta hydrolase fold. This domain is common to a number of hydrolytic enzymes of widely differing phylogenetic origins and catalytic functions. [provided by RefSeq, Jul 2008]
Source : In Vitro Cell Free System
Species : Human
Tag : GST
Molecular Mass : 70.07 kDa
Protein Length : 405 amino acids
AA Sequence : MLSSFLSPQN GTWADTFSLL LALAVALYLG YYWACVLQRP RLVAGPQFLA FLEPHCSITT ETFYPTLWCF EGRLQSIFQV LLQSQPLVLY QSDILQTPDG GQLLLDWAKQ PDSSQDPDPT TQPIVLLLPG ITGSSQETYV LHLVNQALRD GYQAVVFNNR GCRGEELRTH RAFCASNTED LETVVNHIKH RYPQAPLLAV GISFGGILVL NHLAQARQAA GLVAALTLSA CWDSFETTRS LETPLNSLLF NQPLTAGLCQ LVERNRKVIE KVVDIDFVLQ ARTIRQFDER YTSVAFGYQD CVTYYKAASP RTKIDAIRIP VLYLSAADDP FSPVCALPIQ AAQHSPYVAL LITARGGHIG FLEGLLPWQH WYMSRLLHQY AKAIFQDPEG LPDLRALLPS EDRNS
Applications : Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
Storage : Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
Storage Buffer : 50 mM Tris-HCl, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Gene Name : ABHD1 abhydrolase domain containing 1 [ Homo sapiens ]
Official Symbol : ABHD1
Synonyms : ABHD1; abhydrolase domain containing 1; abhydrolase domain-containing protein 1; FLJ36128; LABH1; lung alpha/beta hydrolase 1
Gene ID : 84696
mRNA Refseq : NM_032604
Protein Refseq : NP_115993
MIM : 612195
UniProt ID : Q96SE0

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (10)

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What does the expression of steady-state ABHD1 and Sec12 mRNA in both tissues and cells suggest? 09/20/2021

It indicated that these two genes are co-expressed in a spatial manner, however, their expression may be separated in a temporal manner. 

What disease could be easily got by children if ABHD1 and DOK6 occur mutations? 06/01/2021

Hirschsprung disease.

List one biological function of the ABHD1 and provide the reaction equation if possible. 12/01/2020

Acylglycerol lipase activity. Catalysis of the reaction: H2O + acylglycerol = a fatty acid + glycerol.

What is the difference between Sec12 and ABHD, even though both of them were expressed in all adult tissues and cells? 05/01/2020

ABHD1 levels were highest in skeletal muscle, testis and liver, but over a thousand-fold lower in spleen and fibroblasts, whereas the level of expression of Sec12 was more constant between tissues and cells types, varying less than a hundred-fold.

One study find that mammalian ABHD1 and Sec12 genes contain a conserved 42 bp overlap in their 3'UTR, what does this imply? 03/11/2020

It implied that Sec12 and ABHD1 proteins do not share any sequence homology, but it is possible that they could be functionally related.

List three biological process of the ABHD1 protein? 10/10/2019

Cellular lipid metabolic process, medium-chain fatty acid biosynthetic process, and medium-chain fatty acid catabolic process

Where is the homologs of the ABHD1 gene exist? 04/03/2019

The ABHD1 gene is existed in chimpanzee, K.lactis, E.gossypii, M.oryzae, N.crassa, A.thaliana, etc.

What is the mapping of the ABHD1 gene? 04/09/2018

By genomic sequence analysis, mapped the ABHD1 gene to chromosome 2p23.3.  

what kind of buffer solution of the ABHD1 antibody we need? 01/13/2018

20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Researchers found that the downregulation of ABHD1 levels leads to a significant reduction in mitochondrial translation in vivo. What does this result indicate? 12/12/2017

It indicating the crucial role of modifications induced by ABHD1 in the function of mitochondrial transfer RNA for Met (mt‐tRNAMet), and a series of other modifications occur in mt‐tRNAMet.

Customer Reviews (3)

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Reviews
01/19/2020

    Very effective.

    11/10/2018

      It provide best manufacturing services and products, thanks!

      08/10/2018

        Excellent quality products!

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