Recombinant Full Length Human ABLIM1 Protein, GST-tagged

• Cat.No.: ABLIM1-790HF
• Product Overview: Human ABLIM1 full-length ORF ( AAH02448.1, 1 a.a. - 401 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: This gene encodes a cytoskeletal LIM protein that binds to actin filaments via a domain that is homologous to erythrocyte dematin. LIM domains, found in over 60 proteins, play key roles in the regulation of developmental pathways. LIM domains also function as protein-binding interfaces, mediating specific protein-protein interactions. The protein encoded by this gene could mediate such interactions between actin filaments and cytoplasmic targets. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]
• Source: In Vitro Cell Free System
• Species: Human
• Tag: GST
• Molecular Mass: 72.5 kDa
• Protein Length: 401 amino acids
• AA Sequence: MFTEGEEMYL QGSTVWHPDC KQSTKTEEKL RAKVDNEILD YKDLAAIPKV KAIYDIERPD LITYEPFYTS GYDDKQERQS LGESPRTLSP TPSAEGYQDV RDRMIHRSTS QGSINSPVYS RHSYTPTTSR SPQHFHRPDQ GINIYRKPPI YKQHAALAAQ SKSSEDIIKF SKFPAAQAPD PSETPKIETD HWPGPPSFAV VGPDMKRRSS GREEDDEELL RRRQLQEEQL MKLNSGLGQL ILKEEMEKES RERSSLLASR YDSPINSASH IPSSKTASLP GYGRNGLHRP VSTDFAQYNS YGDVSGGVRD YQTLPDGHMP AMRMDRGVSM PNMLEPKIFP YEMLMVTNRG RNKILREVDR TRLERHLAPE VFREIFGMSI QEFDRLPLWR RNDMKKKAKL F
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCl, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: ABLIM1 actin binding LIM protein 1 [ Homo sapiens ]
• Official Symbol: ABLIM1
• Synonyms: ABLIM1; actin binding LIM protein 1; ABLIM, LIMAB1; actin-binding LIM protein 1; abLIM; limatin; actin-binding double-zinc-finger protein; actin-binding LIM protein family member 1; ABLIM; LIMAB1; LIMATIN; abLIM-1; MGC1224; FLJ14564; KIAA0059; DKFZp781D0148
• Gene ID: 3983
• mRNA Refseq: NM_001003407
• Protein Refseq: NP_001003407
• MIM: 602330
• UniProt ID: O14639

Reviews

01/21/2022

cost-effective and high-quality.

10/10/2020

The product quality is very good. Online consulting service can help you quickly find your target, very efficient.

Q&As

How to store the product after receiving it?

Upon delivery aliquot and store at -80 centigrade. Avoid freeze/thaw cycles.

Where was ABLIM1 first discovered?

ABLIM-1 was originally found in human retina as well as in the sarcomeres of murine cardiac tissue and was postulated to regulate actin-dependent signaling.

Will there be an interaction between LDOC1 and ABLIM1?

Yes.ABLIM1 has been shown to interact with LDOC1.

Does the endotoxin in your product meet the requirements?

We will remove endotoxin according to customer's requirements and verify by LAL method.

What is the purity of the product ABLIM1-03HF?

All of our products can be customized, and protein products of different purity can be delivered according to different needs of customers.

Where is ABLIM1 localized?

ABLIM1 localization in cytoplasm and cytoskeleton.

What are the functions of ABLIM1?

ABLIM1 may act as scaffold protein. It may play a role in the retina development and in axon guidance.

Is ABLIM3 a paralog of ABLIM1?

yes, it is.

Which cellular pathways are involved in Actin Binding LIM Protein 1?

Among its related pathways are Nervous system development and Netrin-1 signaling.

Which diseases are associated with ABLIM1?

Diseases associated with ABLIM1 include Spermatogenic Failure, Y-Linked, 2