Recombinant Full Length Human ABTB1 Protein, GST-tagged

• Cat.No.: ABTB1-869HF
• Product Overview: Human ABTB1 full-length ORF ( NP_115937.1, 1 a.a. - 336 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: This gene encodes a protein with an ankyrin repeat region and two BTB/POZ domains, which are thought to be involved in protein-protein interactions. Expression of this gene is activated by the phosphatase and tensin homolog, a tumor suppressor. Alternate splicing results in three transcript variants. [provided by RefSeq, Mar 2010]
• Source: In Vitro Cell Free System
• Species: Human
• Tag: GST
• Molecular Mass: 64 kDa
• Protein Length: 336 amino acids
• AA Sequence: MLDTKWKGKS VVVLRHPLIN PVAFGALLQY LYTGRLDIGV EHVSDCERLA KQCQLWDLLS DLEAKCEKVS EFVASKPGTC VKVLTIEPPP ADPRLREDMA LLADCALPPE LRGDLWELPF PCPDGFNSCP DICFRVAGCS FLCHKAFFCG RSDYFRALLD DHFRESEEPA TSGGPPAVTL HGISPDVFTH VLYYMYSDHT ELSPEAAYDV LSVADMYLLP GLKRLCGRSL AQMLDEDTVV GVWRVAKLFR LARLEDQCTE YMAKVIEKLV EREDFVEAVK EEAAAVAARQ ETDSIPLVDD IRFHVASTVQ TYSAIEEAQQ RLRALEDLLV SIGLDC
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCl, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: ABTB1 ankyrin repeat and BTB (POZ) domain containing 1 [ Homo sapiens ]
• Official Symbol: ABTB1
• Synonyms: ABTB1; ankyrin repeat and BTB (POZ) domain containing 1; ankyrin repeat and BTB/POZ domain-containing protein 1; BPOZ; Btb3; EF1ABP; elongation factor 1A-binding protein; BTB3; PP2259; MGC20585
• Gene ID: 80325
• mRNA Refseq: NM_032548
• Protein Refseq: NP_115937
• MIM: 608308
• UniProt ID: Q969K4

Reviews

02/16/2021

Performs exceptionally well in protein crystallization experiments, improving crystal quality and yield.

07/07/2018

Provides highly accurate quantification information in mass spectrometry analysis.

05/08/2017

Highly sensitive in bioactivity assays, accurately detecting the activity and concentration of bioactive factors.

Q&As

What is the function of the protein encoded by the ABTB1 gene?

The ABTB1 protein plays an important role in cell proliferation and apoptosis, and is involved in a variety of cellular signaling pathways.

Are there any disease-associated mutations in the ABTB1 gene?

No disease-associated mutations in the ABTB1 gene have been identified so far.

What factors affect the expression of the ABTB1 gene?

The expression of the ABTB1 gene is influenced by various factors, including epigenetics, transcription factors, and cellular signaling.

On which chromosome is the ABTB1 gene located?

The ABTB1 gene is located on chromosome 13 in the human genome.

In which tissues is the ABTB1 protein expressed?

The ABTB1 protein is widely expressed in various tissues, including the liver, lungs, heart, kidneys, brain, and intestines.

What are the structural features of the ABTB1 protein?

The ABTB1 protein is composed of multiple ankyrin repeats and a BTB domain, which enable it to function in multiple signaling pathways.

In which cellular processes does the ABTB1 gene play a role?

The ABTB1 gene is involved in multiple cellular processes, including the cell cycle, apoptosis, transcriptional regulation, and DNA repair.

What is ankyrin repeat and BTB domain containing 1 gene (ABTB1)?

ABTB1 is a gene that encodes a protein containing ankyrin repeats and a BTB (Broad-Complex, Tramtrack and Bric a brac) domain.

In which diseases does the ABTB1 protein play a role?

The ABTB1 protein plays a role in the development of diseases such as cancer, neurological disorders, and autoimmune diseases.

Does the ABTB1 gene interact with other genes?

The ABTB1 gene interacts with many other genes, including p53, NF-κB, and STAT3.