Recombinant Full Length Human ACAA1 Protein, GST-tagged
Cat.No. : | ACAA1-870HF |
Product Overview : | Human ACAA1 full-length ORF ( NP_001598.1, 1 a.a. - 424 a.a.) recombinant protein with GST-tag at N-terminal. |
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Description : | This gene encodes an enzyme operative in the beta-oxidation system of the peroxisomes. Deficiency of this enzyme leads to pseudo-Zellweger syndrome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2008] |
Source : | In Vitro Cell Free System |
Species : | Human |
Tag : | GST |
Molecular Mass : | 70.7 kDa |
Protein Length : | 424 amino acids |
AA Sequence : | MQRLQVVLGH LRGPADSGWM PQAAPCLSGA PQASAADVVV VHGRRTAICR AGRGGFKDTT PDELLSAVMT AVLKDVNLRP EQLGDICVGN VLQPGAGAIM ARIAQFLSDI PETVPLSTVN RQCSSGLQAV ASIAGGIRNG SYDIGMACGV ESMSLADRGN PGNITSRLME KEKARDCLIP MGITSENVAE RFGISREKQD TFALASQQKA ARAQSKGCFQ AEIVPVTTTV HDDKGTKRSI TVTQDEGIRP STTMEGLAKL KPAFKKDGST TAGNSSQVSD GAAAILLARR SKAEELGLPI LGVLRSYAVV GVPPDIMGIG PAYAIPVALQ KAGLTVSDVD IFEINEAFAS QAAYCVEKLR LPPEKVNPLG GAVALGHPLG CTGARQVITL LNELKRRGKR AYGVVSMCIG TGMGAAAVFE YPGN |
Applications : | Enzyme-linked Immunoabsorbent Assay Western Blot (Recombinant protein) Antibody Production Protein Array |
Storage : | Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing. |
Storage Buffer : | 50 mM Tris-HCl, 10 mM reduced Glutathione, pH=8.0 in the elution buffer. |
Gene Name : | ACAA1 acetyl-CoA acyltransferase 1 [ Homo sapiens ] |
Official Symbol : | ACAA1 |
Synonyms : | ACAA1; acetyl-CoA acyltransferase 1; acetyl Coenzyme A acyltransferase 1; 3-ketoacyl-CoA thiolase, peroxisomal; peroxisomal 3 oxoacyl Coenzyme A thiolase; beta-ketothiolase; peroxisomal 3-oxoacyl-CoA thiolase; acetyl-Coenzyme A acyltransferase 1; peroxisomal 3-oxoacyl-Coenzyme A thiolase; ACAA; THIO; PTHIO |
Gene ID : | 30 |
mRNA Refseq : | NM_001130410 |
Protein Refseq : | NP_001123882 |
MIM : | 604054 |
UniProt ID : | P09110 |
Products Types
◆ Recombinant Protein | ||
ACAA1-302H | Recombinant Human ACAA1 Protein (27-331 aa), His-SUMO-tagged | +Inquiry |
ACAA1-251H | Recombinant Human ACAA1 Protein, His (Fc)-Avi-tagged | +Inquiry |
ACAA1-408H | Recombinant Human ACAA1 Protein, MYC/DDK-tagged, C13 and N15-labeled | +Inquiry |
ACAA1-9260H | Recombinant Human ACAA1, GST-tagged | +Inquiry |
ACAA1-0465H | Recombinant Human ACAA1 Protein (Gly182-Asn424), N-His-tagged | +Inquiry |
◆ Lysates | ||
ACAA1-9119HCL | Recombinant Human ACAA1 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (10)
Ask a questionModulating its activity could potentially treat metabolic disorders or enhance ketone body production.
It is a dimeric protein with a helix-turn-helix motif.
It plays a crucial role in beta-oxidation of fatty acids and ketone body synthesis.
It catalyzes the transfer of an acyl group from acyl-CoA to CoA.
It interacts with other enzymes in the beta-oxidation pathway, including acyl-CoA dehydrogenases and enoyl-CoA hydratases.
Its expression is regulated by transcription factors, hormones, and metabolic signals.
It is involved in the metabolism of long-chain fatty acids, branched-chain amino acids, and isoprenoids.
Deficiency can lead to metabolic disorders, such as hypoketotic hypoglycemia, while overexpression may increase ketone body production.
It is expressed in various tissues, including liver, adipose tissue, and muscle.
Dysregulation of its activity may contribute to the development of metabolic diseases such as diabetes and obesity.
Customer Reviews (2)
Write a reviewProvides high signal-to-noise ratio and low background in detection of the target protein in various assays.
Highly effective in blocking the activity of the target protein in functional studies.
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