Recombinant Full Length Human ACP6 Protein, GST-tagged
Cat.No. : | ACP6-803HF |
Product Overview : | Human ACP6 full-length ORF ( NP_057445.2, 1 a.a. - 428 a.a.) recombinant protein with GST-tag at N-terminal. |
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Description : | This gene encodes a member of the histidine acid phosphatase protein family. The encoded protein hydrolyzes lysophosphatidic acid, which is involved in G protein-coupled receptor signaling, lipid raft modulation, and in balancing lipid composition within the cell. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2016] |
Source : | In Vitro Cell Free System |
Species : | Human |
Tag : | GST |
Molecular Mass : | 75.3 kDa |
Protein Length : | 428 amino acids |
AA Sequence : | MITGVFSMRL WTPVGVLTSL AYCLHQRRVA LAELQEADGQ CPVDRSLLKL KMVQVVFRHG ARSPLKPLPL EEQVEWNPQL LEVPPQTQFD YTVTNLAGGP KPYSPYDSQY HETTLKGGMF AGQLTKVGMQ QMFALGERLR KNYVEDIPFL SPTFNPQEVF IRSTNIFRNL ESTRCLLAGL FQCQKEGPII IHTDEADSEV LYPNYQSCWS LRQRTRGRRQ TASLQPGISE DLKKVKDRMG IDSSDKVDFF ILLDNVAAEQ AHNLPSCPML KRFARMIEQR AVDTSLYILP KEDRESLQMA VGPFLHILES NLLKAMDSAT APDKIRKLYL YAAHDVTFIP LLMTLGIFDH KWPPFAVDLT MELYQHLESK EWFVQLYYHG KEQVPRGCPD GLCPLDMFLN AMSVYTLSPE KYHALCSQTQ VMEVGNEE |
Applications : | Enzyme-linked Immunoabsorbent Assay Western Blot (Recombinant protein) Antibody Production Protein Array |
Storage : | Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing. |
Storage Buffer : | 50 mM Tris-HCl, 10 mM reduced Glutathione, pH=8.0 in the elution buffer. |
Gene Name : | ACP6 acid phosphatase 6, lysophosphatidic [ Homo sapiens ] |
Official Symbol : | ACP6 |
Synonyms : | ACP6; acid phosphatase 6, lysophosphatidic; lysophosphatidic acid phosphatase type 6; ACPL1; LPAP; acid phosphatase like 1; acid phosphatase-like protein 1; PACPL1 |
Gene ID : | 51205 |
mRNA Refseq : | NM_016361 |
Protein Refseq : | NP_057445 |
MIM : | 611471 |
UniProt ID : | Q9NPH0 |
Products Types
◆ Recombinant Protein | ||
Acp6-1504M | Recombinant Mouse Acp6 Protein, Myc/DDK-tagged | +Inquiry |
ACP6-265M | Recombinant Mouse ACP6 Protein, His (Fc)-Avi-tagged | +Inquiry |
ACP6-44R | Recombinant Rhesus Macaque ACP6 Protein, His (Fc)-Avi-tagged | +Inquiry |
Acp6-7856R | Recombinant Rat Acp6 protein, His & T7-tagged | +Inquiry |
ACP6-449H | Active Recombinant Human ACP6, His-tagged | +Inquiry |
◆ Lysates | ||
ACP6-9081HCL | Recombinant Human ACP6 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (10)
Ask a questionChromosome 1q21.1 Deletion Syndrome, Duodenal Atresi, and Chromosome 1p36 Deletion Syndrome.
Highly expressed in kidney, heart, small intestine, muscle, liver, prostate, testis, ovary and weakly expressed in thymus and colon.
This gene is overexpressed in Salivary gland, oral epithelium, and gallbladder.
Cytoplasm, Mitochondrion, and Mitochondrial matrix
Among its related pathways are Glycerophospholipid biosynthesis and Metabolism.
Increased caccinia virus infection.
Has highest activity with lysophosphatidic acid containing myristate (C14:0), monounsaturated oleate (C18:1) or palmitate (C16:0), and lower activity with C18:0 and C6:0 lysophosphatidic acid.
Lysophosphatidic acid phosphatase activity is used to detect and to quantify irregular levels of LPAs on a cell's surface.[12] LPAs are receptor-active mediators that promote cell motility, cell growth and cell survival. There is clear evidence that cancerous ovarian cells have an increased level of LPA concentrations on their cell surfaces.
We can apply violin plots and receiver’s operating characteristics (ROC) curves.
It is suggested that ACP6 gene overexpressed in HCC, which present that ACP6 gene could be a clinico-pathological indicator of hepatocellular carcinoma (HCC).
Customer Reviews (5)
Write a reviewI am very very happy with this recombinant protein! Was definitely worth getting the more expensive one!
The website of this produce provide detaield informations to guide me use it. Great!
It is a great product, worked as expected.
The product is good.
It works the way it's supposed to and you can't beat the price.
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