Recombinant Full Length Human ACTN2 Protein, C-Flag-tagged
Cat.No. : | ACTN2-968HFL |
Product Overview : | Recombinant Full Length Human ACTN2 Protein, fused to Flag-tag at C-terminus, was expressed in Mammalian cells. |
- Specification
- Gene Information
- Related Products
- Download
Description : | Alpha actinins belong to the spectrin gene superfamily which represents a diverse group of cytoskeletal proteins, including the alpha and beta spectrins and dystrophins. Alpha actinin is an actin-binding protein with multiple roles in different cell types. In nonmuscle cells, the cytoskeletal isoform is found along microfilament bundles and adherens-type junctions, where it is involved in binding actin to the membrane. In contrast, skeletal, cardiac, and smooth muscle isoforms are localized to the Z-disc and analogous dense bodies, where they help anchor the myofibrillar actin filaments. This gene encodes a muscle-specific, alpha actinin isoform that is expressed in both skeletal and cardiac muscles. Several transcript variants encoding different isoforms have been found for this gene. |
Source : | Mammalian cells |
Species : | Human |
Tag : | Flag |
Form : | 25 mM Tris HCl, pH 7.3, 100 mM glycine, 10% glycerol. |
Molecular Mass : | 103.7 kDa |
AA Sequence : | MNQIEPGVQYNYVYDEDEYMIQEEE WDRDLLLDPAWEKQQRKTFTAWCNS HLRKAGTQIENIEEDFRNGL KLMLLLEVISGERLPKPDRGKMRFH KIANVNKALDYIASKGVKLVSIGAE EIVDGNVKMTLGMIWTIILR FAIQDISVEETSAKEGLLLWCQRKT APYRNVNIQNFHTSWKDGLGLCALI HRHRPDLIDYSKLNKDDPIG NINLAMEIAEKHLDIPKMLDAEDIV NTPKPDERAIMTYVSCFYHAFAGAE QAETAANRICKVLAVNQENE RLMEEYERLASELLEWIRRTIPWLE NRTPEKTMQAMQKKLEDFRDYRRKH KPPKVQEKCQLEINFNTLQT KLRISNRPAFMPSEGKMVSDIAGAW QRLEQAEKGYEEWLLNEIRRLERLE HLAEKFRQKASTHETWAYGK EQILLQKDYESASLTEVRALLRKHE AFESDLAAHQDRVEQIAAIAQELNE LDYHDAVNVNDRCQKICDQW DRLGTLTQKRREALERMEKLLETID QLHLEFAKRAAPFNNWMEGAMEDLQ DMFIVHSIEEIQSLITAHEQ FKATLPEADGERQSIMAIQNEVEKV IQSYNIRISSSNPYSTVTMDELRTK WDKVKQLVPIRDQSLQEELA RQHANERLRRQFAAQANAIGPWIQN KMEEIARSSIQITGALEDQMNQLKQ YEHNIINYKNNIDKLEGDHQ LIQEALVFDNKHTNYTMEHIRVGWE LLLTTIARTINEVETQILTRDAKGI TQEQMNEFRASFNHFDRRKN GLMDHEDFRACLISMGYDLGEAEFA RIMTLVDPNGQGTVTFQSFIDFMTR ETADTDTAEQVIASFRILAS DKPYILAEELRRELPPDQAQYCIKR MPAYSGPGSVPGALDYAAFSSALYG ESDLTRTRPLEQKLISEEDLAANDI LDYKDDDDKV |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining. |
Stability : | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
Storage : | Store at -80 centigrade. |
Concentration : | >50 ug/mL as determined by microplate BCA method. |
Preparation : | Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps. |
Protein Pathways : | Adherens junction, Arrhythmogenic right ventricular cardiomyopathy (ARVC), Focal adhesion, Leukocyte transendothelial migration, Regulation of actin cytoskeleton, Systemic lupus erythematosus, Tight junction |
Gene Name : | ACTN2 actinin alpha 2 [ Homo sapiens (human) ] |
Official Symbol : | ACTN2 |
Synonyms : | MPD6; CMH23; CMD1AA; MYOCOZ |
Gene ID : | 88 |
mRNA Refseq : | NM_001103.4 |
Protein Refseq : | NP_001094.1 |
MIM : | 102573 |
UniProt ID : | P35609 |
Products Types
◆ Recombinant Protein | ||
ACTN2-1023H | Recombinant Human ACTN2 Protein, MYC/DDK-tagged | +Inquiry |
ACTN2-271H | Recombinant Human ACTN2 Protein, His (Fc)-Avi-tagged | +Inquiry |
Actn2-526M | Recombinant Mouse Actn2 Protein, MYC/DDK-tagged | +Inquiry |
ACTN2-6875C | Recombinant Chicken ACTN2 | +Inquiry |
Actn2-539M | Recombinant Mouse Actn2 Protein, His-tagged | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Inquiry
- Q&As
- Reviews
Q&As (0)
Ask a questionAsk a Question for All ACTN2 Products
Required fields are marked with *
My Review for All ACTN2 Products
Required fields are marked with *
0
Inquiry Basket