Recombinant Full Length Human ADHFE1 Protein, GST-tagged
Cat.No. : | ADHFE1-944HF |
Product Overview : | Human ADHFE1 full-length ORF ( NP_653251.1, 1 a.a. - 419 a.a.) recombinant protein with GST-tag at N-terminal. |
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Description : | The ADHFE1 gene encodes hydroxyacid-oxoacid transhydrogenase (EC 1.1.99.24), which is responsible for the oxidation of 4-hydroxybutyrate in mammalian tissues (Kardon et al., 2006 [PubMed 16616524]).[supplied by OMIM, Mar 2008] |
Source : | In Vitro Cell Free System |
Species : | Human |
Tag : | GST |
Molecular Mass : | 71.6 kDa |
Protein Length : | 419 amino acids |
AA Sequence : | MAVSNIRYGA AVTKEVGMDL KNMGAKNVCL MTDKNLSKLP PVQVAMDSLV KNGIPFTVYD NVRVEPTDSS FMEAIEFAQK GAFDAYVAVG GGSTMDTCKA ANLYASSPHS DFLDYVSAPI GKGKPVSVPL KPLIAVPTTS GTGSETTGVA IFDYEHLKVK IGITSRAIKP TLGLIDPLHT LHMPARVVAN SGFDVLCHAL ESYTTLPYHL RSPCPSNPIT RPAYQGSNPI SDIWAIHALR IVAKYLKRAV RNPDDLEARS HMHLASAFAG IGFGNAGVHL CHGMSYPISG LVKMYKAKDY NVDHPLVPHG LSVVLTSPAV FTFTAQMFPE RHLEMAEILG ADTRTARIQD AGLVLADTLR KFLFDLDVDD GLAAVGYSKA DIPALVKGTL PQERVTKLAP RPQSEEDLAA LFEASMKLY |
Applications : | Enzyme-linked Immunoabsorbent Assay Western Blot (Recombinant protein) Antibody Production Protein Array |
Storage : | Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing. |
Storage Buffer : | 50 mM Tris-HCl, 10 mM reduced Glutathione, pH=8.0 in the elution buffer. |
Gene Name : | ADHFE1 alcohol dehydrogenase, iron containing, 1 [ Homo sapiens ] |
Official Symbol : | ADHFE1 |
Synonyms : | ADHFE1; alcohol dehydrogenase, iron containing, 1; hydroxyacid-oxoacid transhydrogenase, mitochondrial; ADHFe1; FLJ32430; alcohol dehydrogenase 8; Fe-containing alcohol dehydrogenase 1; alcohol dehydrogenase iron-containing protein 1; HOT; ADH8; HMFT2263; MGC48605 |
Gene ID : | 137872 |
mRNA Refseq : | NM_144650 |
Protein Refseq : | NP_653251 |
MIM : | 611083 |
UniProt ID : | Q8IWW8 |
Products Types
◆ Recombinant Protein | ||
ADHFE1-346M | Recombinant Mouse ADHFE1 Protein, His (Fc)-Avi-tagged | +Inquiry |
ADHFE1-183R | Recombinant Rat ADHFE1 Protein, His (Fc)-Avi-tagged | +Inquiry |
ADHFE1-1358M | Recombinant Mouse ADHFE1 Protein | +Inquiry |
ADHFE1-527R | Recombinant Rat ADHFE1 Protein | +Inquiry |
ADHFE1-355H | Recombinant Human ADHFE1 Protein, GST-tagged | +Inquiry |
◆ Lysates | ||
ADHFE1-32HCL | Recombinant Human ADHFE1 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (10)
Ask a questionADHFE1 has the potential to interact with other proteins or participate in protein complexes, indicating its involvement in complex cellular processes.
ADHFE1 exhibits a specific subcellular localization, and its dynamic changes in response to cellular signals or stimuli suggest a regulatory role in cellular processes.
ADHFE1 plays a role in cellular metabolism and contributes to specific biological processes, highlighting its functional significance in maintaining cellular homeostasis.
Genetic variations or polymorphisms in the ADHFE1 gene provide insights into individual differences and their impact on ADHFE1 expression or enzymatic function.
Post-translational modifications on ADHFE1 can affect its stability, enzymatic activity, or interaction with other molecules, revealing their regulatory role in its function.
ADHFE1 deficiency or overexpression can lead to cellular or physiological phenotypes, highlighting its essential role and the underlying mechanisms.
ADHFE1's activity can be modulated by known regulatory factors or cofactors, highlighting the complexity of its functional regulation.
ADHFE1 possesses enzymatic activity and catalyzes specific reactions, transforming specific substrates into products.
ADHFE1 represents a potential target for pharmacological modulation, offering possibilities for therapeutic interventions in relevant conditions or diseases.
ADHFE1 shows a tissue-specific expression pattern, and its developmental or spatial regulation suggests specific roles in different tissues or stages.
Customer Reviews (2)
Write a reviewHighly efficient in directing protein translocation to specific cellular compartments.
Displays excellent stability and compatibility with different detergents in membrane protein solubilization.
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