Recombinant Full Length Human AGBL4 Protein, GST-tagged

• Cat.No.: AGBL4-996HF
• Product Overview: Human AGBL4 full-length ORF ( ADR83127.1, 1 a.a. - 268 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: AGBL4 (ATP/GTP Binding Protein Like 4) is a Protein Coding gene. Diseases associated with AGBL4 include Macular Degeneration, Age-Related, 1. GO annotations related to this gene include tubulin binding and metallocarboxypeptidase activity. An important paralog of this gene is AGBL5.
• Source: In Vitro Cell Free System
• Species: Human
• Tag: GST
• Molecular Mass: 29.5 kDa
• Protein Length: 268 amino acids
• AA Sequence: MDYFFREQLG QSVQQRKLDL LTITSPDNLR EGAEQKVVFI TGRVHPGETP SSFVCQGIID FLVSQHPIAC VLREYLVFKI APMLNPDGVY LGNYRCSLMG FDLNRHWLDP SPWVHPTLHG VKQLIVQMYN DPKTSLEFYI DIHAHSTMMN GFMYGNIFED EERFQRQAIF PKLLCQNAED FSYSSTSFNR DAVKAGTGRR FLGGLLDHTS YCYTLEVSFY SYIISGTTAA VPYTEEACIL SPHPALGQPS SSREYPSLTG QELGPQLR
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCl, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: AGBL4 ATP/GTP binding protein-like 4 [ Homo sapiens ]
• Official Symbol: AGBL4
• Synonyms: AGBL4; ATP/GTP binding protein-like 4; cytosolic carboxypeptidase 6; FLJ14442; ATP/GTP-binding protein-like 4; CCP6
• Gene ID: 84871
• mRNA Refseq: NM_032785
• Protein Refseq: NP_116174
• MIM: 616476
• UniProt ID: Q5VU57

Reviews

08/08/2021

 The product’s innovative traits allowed us to explore previously unknown cellular processes.

08/02/2021

It’s consistency allowed us to draw meaningful conclusions.

06/30/2017

Treatment with Protein AGBL4 consistently resulted in enhanced cell adhesion.

02/19/2017

The product’s consistent outcomes reinforced the reproducibility of our scientific investigations.

10/14/2016

It's high quality yielded reproducible protein crystallization.

Q&As

Does AGBL4 play a role in autophagy?

AGBL4's connection to autophagy, cellular self-degradation, is being explored.

Is AGBL4 critical for normal cellular development?

AGBL4's contributions to cellular development are being investigated, suggesting importance.

Are there links between AGBL4 variations and diseases?

Some evidence suggests that AGBL4 mutations could relate to specific diseases.

Where is AGBL4 primarily located in cells?

AGBL4 is mainly situated in the cytoplasm, contributing to cellular functions.

Can AGBL4 be targeted for therapeutic purposes?

Researchers are investigating AGBL4's potential as a therapeutic target.

Could AGBL4 impact protein quality control?

AGBL4's functions might contribute to maintaining proper protein quality within cells.

Does AGBL4 interact with other cellular proteins?

AGBL4's interactions with diverse proteins contribute to its cellular roles.

How is AGBL4's structural makeup characterized?

AGBL4's structure includes domains that offer insights into its functional roles.

Are animal models utilized in AGBL4 research?

Animal models help understand AGBL4's functions and potential implications.

Is AGBL4's role in cellular regulation well-defined?

While tied to protein processes, AGBL4's complete regulatory roles continue to emerge.

What are the roles of AGBL4 in cells?

AGBL4 is implicated in cellular processes, including potential involvement in protein regulation.

Where is AGBL4 predominantly located within cells?

AGBL4 is typically located in the cellular cytoplasm, contributing to cellular tasks.

How does AGBL4 influence cellular balance?

AGBL4's functions likely play a role in maintaining cellular equilibrium.

What's distinctive about AGBL4's three-dimensional structure?

AGBL4's structural features offer insights into its potential functional roles.

Does AGBL4 exhibit enzymatic behavior?

Yes, AGBL4 displays metalloprotease activity, allowing peptide bond cleavage in proteins.

How does AGBL4 differ from other ATP/GTP-binding proteins?

AGBL4's unique attributes and functions distinguish it within the binding protein family.

What defines the AGBL4 protein?

AGBL4 refers to "ATP/GTP-binding protein-like 4," with roles in diverse cellular processes.

Can external factors regulate AGBL4 expression?

Yes, AGBL4 expression and activity can be influenced by cellular cues.

Does AGBL4 appear in multiple cell types?

Yes, AGBL4's presence spans various cell types, suggesting widespread involvement.

How does AGBL4 respond to cellular stress?

AGBL4's response to stress is a topic of active investigation.