Recombinant Full Length Human Androgen-Dependent Tfpi-Regulating Protein(Adtrp),Nanodisc Protein, His&Myc-Tagged

• Cat.No.: RFL16805HF
• Product Overview: Recombinant Full Length Human Androgen-dependent TFPI-regulating protein(ADTRP),Nanodisc Protein (Q96IZ2) (1-230aa), fused to N-terminal 10xHis tag and C-terminal Myc tag, was expressed in E. coli.

Specification

• Source: E.coli expression system
• Species: Homo sapiens (Human)
• Tag: His&Myc
• Form: Lyophilized powder
• Protein Length: Full Length (1-230aa)
• AA Sequence: MTKTSTCIYHFLVLSWYTFLNYYIS QEGKDEVKPKILANGARWKYMTLLN LLLQTIFYGVTCLDDVLKRTKGGKD IKFLTAFRDLLFTTLAFPVSTFVFL AFWILFLYNRDLIYPKVLDTVIPVW LNHAMHTFIFPITLAEVVLRPHSYP SKKTGLTLLAAASIAYISRILWLYF ETGTWVYPVFAKLSLLGLAAFFSLS YVFIASIYLLGEKLNHWKWGDMRQP RKKRK Note: The complete sequence including tag sequence, target protein sequence and linker sequence could be provided upon request.
• Purity: Greater than 90% as determined by SDS-PAGE.
• Notes: Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
• Storage: Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
• Storage Buffer: Tris/PBS-based buffer, 6% Trehalose, pH 8.0
• Reconstitution: We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
• Gene Name: ADTRP
• Synonyms: ADTRP; C6orf105; Androgen-dependent TFPI-regulating protein; Fatty acid esters of hydroxy fatty acids hydrolase ADTRP; FAHFA hydrolase ADTRP
• UniProt ID: Q96IZ2

Gene Information

• Gene Name: ADTRP
• Synonyms: ADTRP; C6orf105; Androgen-dependent TFPI-regulating protein; Fatty acid esters of hydroxy fatty acids hydrolase ADTRP; FAHFA hydrolase ADTRP
• UniProt ID: Q96IZ2

Reviews

06/09/2022

Determining protein-protein interaction interfaces using peptide array assays.

04/18/2022

Characterizing protein-protein interactions involved in cell migration.

11/29/2019

Exploring protein-protein interactions involved in angiogenesis pathways.

Q&As

Are there any known post-translational modifications or regulatory factors that modulate the activity or stability of ADTRP protein?

Post-translational modifications, such as phosphorylation or ubiquitination, and regulatory factors like lipid signals or protein-protein interactions, may modulate the activity or stability of ADTRP protein.

What experimental techniques have been employed to investigate the functional significance of ADTRP protein?

Experimental techniques such as knockout or overexpression studies, as well as cellular and molecular biology approaches, have been employed to investigate the functional significance of ADTRP protein in lipid metabolism and cellular processes.

What are the tissue-specific expression patterns of ADTRP protein and the factors that regulate its expression levels?

ADTRP protein exhibits tissue-specific expression, with higher levels observed in the heart, skeletal muscle, and adipose tissue. Factors involved in its regulation include transcriptional control and tissue-specific signaling pathways.

How is the subcellular localization of ADTRP protein determined, and are there specific mechanisms or targeting sequences involved?

The subcellular localization of ADTRP protein is determined by specific targeting sequences and mechanisms that facilitate its transport and integration into the endoplasmic reticulum membrane.

Are there any specific structural features or domains of ADTRP protein that are critical for its function or interaction with other molecules?

ADTRP protein contains specific structural features, including transmembrane domains and potential lipid-binding motifs, that are critical for its function and interaction with lipid molecules or membrane components.

What is the enzymatic activity of ADTRP protein, and how is it measured or quantified in experimental assays?

The enzymatic activity of ADTRP protein, potentially involved in lipid metabolism, can be measured or quantified using enzymatic assays that assess substrate utilization or product formation.

Are there any genetic variations or mutations in the ADTRP gene that impact the expression or function of ADTRP protein?

Genetic variations or mutations in the ADTRP gene may impact the expression or function of ADTRP protein, potentially contributing to lipid metabolism disorders or cardiovascular diseases.

What is the role of ADTRP protein in specific cellular processes or metabolic pathways?

ADTRP protein is implicated in lipid metabolism and membrane biology, potentially playing a role in lipid droplet formation, lipid storage, or lipid transport processes.

Does ADTRP protein interact with other proteins or participate in protein complexes, and if so, what are the functional implications?

ADTRP protein has been shown to interact with other proteins, such as enzymes involved in lipid metabolism or membrane trafficking, suggesting potential roles in lipid homeostasis and intracellular transport processes.

How does dysregulation or dysfunction of ADTRP protein affect cellular functions or contribute to disease development?

Dysregulation or dysfunction of ADTRP protein may affect cellular lipid homeostasis, leading to imbalances in lipid metabolism and potential contributions to diseases such as obesity or cardiomyopathies.