Recombinant Full Length Human AOC1 Protein, C-Flag-tagged

• Cat.No.: AOC1-2148HFL
• Product Overview: Recombinant Full Length Human AOC1 Protein, fused to Flag-tag at C-terminus, was expressed in Mammalian cells.

Specification

• Description: This gene encodes a metal-binding membrane glycoprotein that oxidatively deaminates putrescine, histamine, and related compounds. The encoded protein is inhibited by amiloride, a diuretic that acts by closing epithelial sodium ion channels. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
• Source: Mammalian cells
• Species: Human
• Tag: Flag
• Form: 25 mM Tris HCl, pH 7.3, 100 mM glycine, 10% glycerol.
• Molecular Mass: 83.4 kDa
• AA Sequence: MPALGWAVAAILMLQTAMAEPSPGT LPRKAGVFSDLSNQELKAVHSFLWS KKELRLQPSSTTTMAKNTVF LIEMLLPKKYHVLRFLDKGERHPVR EARAVIFFGDQEHPNVTEFAVGPLP GPCYMRALSPRPGYQSSWAS RPISTAEYALLYHTLQEATKPLHQF FLNTTGFSFQDCHDRCLAFTDVAPR GVASGQRRSWLIIQRYVEGY FLHPTGLELLVDHGSTDAGHWAVEQ VWYNGKFYGSPEELARKYADGEVDV VVLEDPLPGGKGHDSTEEPP LFSSHKPRGDFPSPIHVSGPRLVQP HGPRFRLEGNAVLYGGWSFAFRLRS SSGLQVLNVHFGGERIAYEV SVQEAVALYGGHTPAGMQTKYLDVG WGLGSVTHELAPGIDCPETATFLDT FHYYDADDPVHYPRALCLFE MPTGVPLRRHFNSNFKGGFNFYAGL KGQVLVLRTTSTVYNYDYIWDFIFY PNGVMEAKMHATGYVHATFY TPEGLRHGTRLHTHLIGNIHTHLVH YRVDLDVAGTKNSFQTLQMKLENIT NPWSPRHRVVQPTLEQTQYS WERQAAFRFKRKLPKYLLFTSPQEN PWGHKRSYRLQIHSMADQVLPPGWQ EEQAITWARYPLAVTKYRES ELCSSSIYHQNDPWDPPVVFEQFLH NNENIENEDLVAWVTVGFLHIPHSE DIPNTATPGNSVGFLLRPFN FFPEDPSLASRDTVIVWPRDNGPNY VQRWIPEDRDCSMPPPFSYNGTYRP V TRTRPLEQKLISEEDLAANDILDYK DDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining.
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade.
• Concentration: >50 ug/mL as determined by microplate BCA method.
• Preparation: Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
• Protein Families: Secreted Protein
• Protein Pathways: Arginine and proline metabolism, Histidine metabolism, Tryptophan metabolism

Gene Information

• Gene Name: AOC1 amine oxidase copper containing 1 [ Homo sapiens (human) ]
• Official Symbol: AOC1
• Synonyms: ABP; DAO; KAO; ABP1; DAO1
• Gene ID: 26
• mRNA Refseq: NM_001091.4
• Protein Refseq: NP_001082.2
• MIM: 104610
• UniProt ID: P19801