Recombinant Full Length Human AP5B1 Protein, GST-tagged

• Cat.No.: AP5B1-3942HF
• Product Overview: Human DKFZp761E198 full-length ORF ( NP_612377.2, 1 a.a. - 552 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: AP5B1 (Adaptor Related Protein Complex 5 Beta 1 Subunit) is a Protein Coding gene. Diseases associated with AP5B1 include Osteogenesis Imperfecta, Type Xii and Mental Retardation, X-Linked Syndromic 5.
• Source: In Vitro Cell Free System
• Species: Human
• Tag: GST
• Molecular Mass: 86.2 kDa
• Protein Length: 552 amino acids
• AA Sequence: MLALKAAFGEALFTAQDEALLLRRL TLAAQHPALPPPTHLFYLHCVLSFP ENWPLGPEGEEAAPLLLGPQLCRGL LPSLLHDPMALLARLHLLCLLCAEE EEEEKGQLPSPRHYLEELLAGLRQR AALDGGPRALATLCFQASYLVACCL AGQPTVLTPLIHGLAQLYQARPMLA PHFVDLLDQVDSELREPLKVVLRQV VVSRPGRDEALCWHLQMLAKVADGD AQSATLNFLQAAAAHCTNWDLQQGL LRVCRALLRAGVRGGLVDLLQVLAR QLEDPDGRDHARLYYILLAHLAAPK LGVALGPSLAAPALASSLVAENQGF VAALMVQEAPALVRLSLGSHRVKGP LPVLKLQPEALEPIYSLELRFRVEG QLYAPLEAVHVPCLCPGRPARPLLL PLQPRCPAPARLDVHALYTTSTGLT CHAHLPPLFVNFADLFLPFPQPPEG AGLGFFEELWDSCLPEGAESRVWCP LGPQGLEGLVSRHLEPFVVVAQPPT SYCVAIHLPPDSKLLLRLEAALADG VPVALRTDDWAVLPLAGDYLRGLAA AV
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCl, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: AP5B1 adaptor related protein complex 5 beta 1 subunit [ Homo sapiens (human) ]
• Official Symbol: AP5B1
• Synonyms: AP5B1; adaptor related protein complex 5 beta 1 subunit; AP-5; PP1030; Adaptor Related Protein Complex 5 Beta 1 Subunit; Adaptor-Related Protein Complex 5 Beta Subunit; Beta5; Adaptor-Related Protein Complex 5, Beta 1 Subunit; AP-5 Complex Subunit Beta-1; AP-5 Complex Subunit Beta; AP-5 complex subunit beta-1; AP-5 complex subunit beta; adaptor-related protein complex 5 beta subunit; beta5
• Gene ID: 91056
• mRNA Refseq: NM_138368
• Protein Refseq: NP_612377
• MIM: 614367
• UniProt ID: Q2VPB7

Reviews

10/01/2022

The stability of AP5B1 was excellent in Western blot analysis and was easy to store.

07/10/2021

The short half-life and high clearance characteristics of AP4S1 enable it to better adapt to changing therapeutic needs and provide patients with more flexible treatment options.

06/13/2021

Stability of AP5B1 is very good, and it can be performed in different types of biological experiments without worrying about the variation and influence of its performance.

12/08/2020

Green production process of AP4S1 is highly commendable, employing the most advanced biotechnology, increasing production efficiency and reducing environmental impact.

Q&As

What is the molecular mechanism of AP5B1 ?

The AP5B1 can bind to cell surface receptors, thereby affecting signal transduction pathways.

What is the prospect of recombinant AP5B1 protein and tumor therapy?

Recombinant AP5B1 has potential therapeutic value, but more studies are needed to verify its efficacy.

What is the application status of AP5B1 in molecular diagnosis?

The detection of AP5B1 is already available in some medical institutions, but it still needs to be further expanded.

What are the biological characteristics of AP5B1 ?

AP5B1 is a regulatory protein that can participate in a variety of cell biological behaviors, such as proliferation, differentiation, apoptosis and other processes.

What are the biochemical characteristics of AP5B1 ?

AP5B1 is a protein molecule with biological activity and specific structural characteristics.

What kind of drugs can AP5B1 be used as?

The AP5B1 has a role in regulating cell division and proliferation, so it can be used to treat diseases such as certain cancers.

What are the side effects of recombinant AP5B1 in the treatment of cancer?

There are no known side effects of AP5B1 in the treatment of cancer, but more clinical studies are needed.

Can AP5B1 induce apoptosis?

AP5B1 can indirectly induce cell apoptosis by regulating cell proliferation and differentiation.

What is the relationship between AP5B1 and apoptosis?

The AP5B1 can participate in the regulation of apoptosis pathway and affect the growth and metastasis of tumor cells.

What is the nature and structure of AP5B1 ?

The AP5B1 is a single polypeptide chain that can form a stable three-dimensional structure under certain conditions.

What are the applications of recombinant AP5B1 in cancer research?

The mechanism of action of AP5B1 is related to tumor growth and metastasis, so it can be used in tumor research and treatment.

What is the diagnostic significance of AP5B1 ?

Testing for recombinant AP5B1 can help diagnose the risk of certain cancers or other diseases.

What are the immunological properties of AP5B1 ?

Recombinant AP5B1 protein is an immunomodulatory molecule that regulates cellular immune responses and inflammatory responses.

What role does recombinant AP5B1 play in the cell cycle?

Recombinant AP5B1 is involved in all phases of the cell cycle, regulating cell division and proliferation.

What is the relationship between recombinant AP5B1 and tumor resistance?

Recombinant protein AP5B1 is associated with drug resistance in tumor cells, so it can be used for drug screening in tumor therapy.

What is the significance of AP5B1 in preclinical studies?

Recombinant AP5B1 protein can be used as an effective molecular target for preclinical research in drug development.

How is the expression of AP5B1 in tumor cells?

The expression of recombinant AP5B1 protein is increased in some tumor cells and is associated with tumor growth and metastasis.

Which genes are associated with recombinant AP5B1?

The AP5B1 is associated with the expression and function of many genes, such as TP53, MCL1, etc.

What is the role of AP5B1 in immunotherapy?

Recombinant AP5B1 protein can be used as a target for immunotherapy to regulate immune response and inflammatory response.

How can AP5B1 be used in drug development?

Recombinant AP5B1 protein can be used for drug screening, optimization and safety evaluation.