Recombinant Full Length Human Apelin Receptor(Aplnr) Protein, His-Tagged

• Cat.No.: RFL-5360HF
• Product Overview: Recombinant Full Length Human Apelin receptor(APLNR) Protein (P35414) (1-380aa), fused to N-terminal His tag, was expressed in E. coli.

Specification

• Source: E.coli expression system
• Species: Homo sapiens (Human)
• Tag: His
• Form: Lyophilized powder
• Protein length: Full Length (1-380)
• AA Sequence: MEEGGDFDNYYGADNQSECEYTDWK SSGALIPAIYMLVFLLGTTGNGLVL WTVFRSSREK RRSADIFIASLAVADLTFVVTLPLW ATYTYRDYDWPFGTFFCKLSSYLIF VNMYASVFCL TGLSFDRYLAIVRPVANARLRLRVS GAVATAVLWVLAALLAMPVMVLRTT GDLENTTKVQ CYMDYSMVATVSSEWAWEVGLGVSS TTVGFVVPFTIMLTCYFFIAQTIAG HFRKERIEGL RKRRRLLSIIVVLVVTFALCWMPYH LVKTLYMLGSLLHWPCDFDLFLMNI FPYCTCISYV NSCLNPFLYAFFDPRFRQACTSMLC CGQSRCAGTSHSSSGEKSASYSSGH SQGPGPNMGK GGEQMHEKSIPYSQETLVVD
• Purity: Greater than 90% as determined by SDS-PAGE.
• Applications: SDS-PAGE
• Notes: Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
• Storage: Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
• Storage Buffer: Tris/PBS-based buffer, 6% Trehalose, pH 8.0
• Reconstitution: We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
• Gene Name: APLNR
• Synonyms: APLNR; AGTRL1; APJ; Apelin receptor; Angiotensin receptor-like 1; G-protein coupled receptor APJ; G-protein coupled receptor HG11
• UniProt ID: P35414

Gene Information

• Gene Name: APLNR
• Synonyms: APLNR; AGTRL1; APJ; Apelin receptor; Angiotensin receptor-like 1; G-protein coupled receptor APJ; G-protein coupled receptor HG11
• UniProt ID: P35414

Reviews

11/24/2020

APLNR is stable under various experimental conditions and is ideal for a variety of application scenarios.

10/22/2020

Green production process of APLNR has the characteristics of high efficiency and environmental protection, and has set a new benchmark for the industry.

04/19/2019

The quantitative accuracy of Western blot is very high, which can accurately determine the content of target protein, indicating that it has high accuracy and low error rate.

03/21/2019

Stability of APLNR is very good, and it can be carried out for long periods of experimental operation without worrying about changes and effects of its performance.

Q&As

When is the best time to treat APLNR ?

At present, there is no specific optimal treatment time, which needs to be determined according to the specific situation and condition of the patient.

Is the efficacy of APLNR long-lasting?

At present, there are no clear results of long-lasting efficacy studies, and more long-term clinical observations and studies are needed.

What are the potential risks and side effects of the use of recombinant APLNR?

As with all drugs, there are risks and side effects associated with the use of APLNR s, such as allergic reactions and bleeding.

Can APLNR be used to prevent disease?

There is no clear way to prevent use, and more research and exploration is needed.

Does APLNR affect blood lipid levels?

According to studies, APLNR can raise HDL cholesterol levels and lower LDL cholesterol levels, thus affecting lipid levels.

Is APLNR recombinant immunogenic?

Studies have shown that the recombinant APLNR protein is not immunogenic in most people.

Is APLNR effective in the treatment of children?

At present, there are no relevant studies to prove whether APLNR is effective in the treatment of children, and more research and exploration are needed.

Can APLNR increase the therapeutic effect through its own repair mechanism?

According to research, APLNR may increase the therapeutic effect by regulating its own repair mechanism.

Is there any difference in the therapeutic effect of APLNR ?

Treatment effectiveness may vary and needs to be evaluated on a patient basis.

How to prepare APLNR ?

Recombinant APLNR proteins can be expressed in microorganisms such as Escherichia coli using genetic engineering technology, and then extracted and purified by protein purification technology.

Has APLNR been used in clinical trials?

Yes, there are currently clinical trials underway to evaluate the safety and efficacy of APLNR.

Which diseases do recombinant APLNR proteins have potential therapeutic effects?

Current studies have shown that APLNR has a potential role in the treatment of diseases such as heart disease, hepatitis, tumors and kidney disease.

Is APLNR effective in the treatment of the elderly?

According to research, recombinant APLNR may be more effective in the treatment of the elderly.

What is the pharmacological principle of APLNR therapy?

The therapeutic effect and targeting mechanism of APLNR is mainly through binding to its receptor APJ and activating related signaling pathways.

How to determine the dose of APLNR in clinical treatment?

There is no specific standard dose, and the dosage is usually determined based on patient conditions and clinical trial results.

Does APLNR have potential for long-term application?

At present, there are no specific studies to show whether the long-term use of APLNR is safe and effective, and long-term clinical observation is needed.

Does APLNR have the potential to be used in combination with drugs?

According to research, the combination of APLNR and other drugs may produce a more significant effect.

Is the price of APLNR expensive?

Based on current research and clinical trials, APLNR s are more expensive, and more research and production are needed to reduce costs.

Can APLNR be used as an alternative to traditional drug therapy?

At present, there is no detailed evidence that APLNR can completely replace traditional drug therapy, and more research and exploration are needed.

Can APLNR be administered orally?

There is currently no specific method of oral administration, but relevant studies may be explored.