Recombinant Full Length Human APLF Protein, GST-tagged
Cat.No. : | APLF-1415HF |
Product Overview : | Human APLF full-length ORF ( NP_775816.1, 1 a.a. - 511 a.a.) recombinant protein with GST-tag at N-terminal. |
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Description : | C2ORF13 is a component of the cellular response to chromosomal DNA single- and double-strand breaks (Iles et al., 2007 [PubMed 17353262]).[supplied by OMIM, Mar 2008] |
Source : | In Vitro Cell Free System |
Species : | Human |
Tag : | GST |
Molecular Mass : | 83.4 kDa |
Protein Length : | 511 amino acids |
AA Sequence : | MSGGFELQPR DGGPRVALAP GETVIGRGPL LGITDKRVSR RHAILEVAGG QLRIKPIHTN PCFYQSSEKS QLLPLKPNLW CYLNPGDSFS LLVDKYIFRI LSIPSEVEMQ CTLRNSQVLD EDNILNETPK SPVINLPHET TGASQLEGST EIAKTQMTPT NSVSFLGENR DCNKQQPILA ERKRILPTWM LAEHLSDQNL SVPAISGGNV IQGSGKEEIC KDKSQLNTTQ QGRRQLISSG SSENTSAEQD TGEECKNTDQ EESTISSKEM PQSFSAITLS NTEMNNIKTN AQRNKLPIEE LGKVSKHKIA TKRTPHKEDE AMSCSENCSS AQGDSLQDES QGSHSESSSN PSNPETLHAK ATDSVLQGSE GNKVKRTSCM YGANCYRKNP VHFQHFSHPG DSDYGGVQIV GQDETDDRPE CPYGPSCYRK NPQHKIEYRH NTLPVRNVLD EDNDNVGQPN EYDLNDSFLD DEEEDYEPTD EDSDWEPGKE DEEKEDVEEL LKEAKRFMKR K |
Applications : | Enzyme-linked Immunoabsorbent Assay; Western Blot (Recombinant protein); Antibody Production; Protein Array |
Storage : | Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing. |
Storage Buffer : | 50 mM Tris-HCl, 10 mM reduced Glutathione, pH=8.0 in the elution buffer. |
Gene Name : | APLF aprataxin and PNKP like factor [ Homo sapiens ] |
Official Symbol : | APLF |
Synonyms : | APLF; aprataxin and PNKP like factor; C2orf13, chromosome 2 open reading frame 13; aprataxin and PNK-like factor; MGC47799; XRCC1-interacting protein 1; PNK and APTX-like FHA protein; aprataxin- and PNK-like factor; apurinic-apyrimidinic endonuclease APLF; PNK and APTX-like FHA domain-containing protein; APFL; PALF; Xip1; C2orf13; FLJ16593 |
Gene ID : | 200558 |
mRNA Refseq : | NM_173545 |
Protein Refseq : | NP_775816 |
MIM : | 611035 |
UniProt ID : | Q8IW19 |
Products Types
◆ Recombinant Protein | ||
APLF-2483H | Recombinant Human APLF Protein, His (Fc)-Avi-tagged | +Inquiry |
Aplf-1661M | Recombinant Mouse Aplf Protein, Myc/DDK-tagged | +Inquiry |
APLF-622M | Recombinant Mouse APLF Protein, His (Fc)-Avi-tagged | +Inquiry |
APLF-13H | Recombinant Human APLF protein, MYC/DDK-tagged | +Inquiry |
APLF-3590B | Recombinant Bovine APLF, His-tagged | +Inquiry |
◆ Lysates | ||
APLF-8793HCL | Recombinant Human APLF 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (19)
Ask a questionAPLF may play a role in adjuvant therapy or targeted therapy in the treatment of immune deficiency diseases.
APLF may be expressed differently in some cancer cells.
APLF may play different mechanisms of action in different cancers, and further research is needed.
APLF is a reaction factor for the single strand structure of DNA.
The expression level of APLF is different in different tissues.
APLF is an important factor in the repair process of DNA double-strand breaks after DNA damage.
APLF may play a role in adjuvant therapy or targeted therapy in cancer therapy.
APLF may play an important role in the process of DNA single strand cleavage repair.
Recombinant APLF proteins may affect the efficiency or manner in which DNA damage is repaired.
APLF may play a role in adjuvant therapy or targeted therapy in tumor immunotherapy.
APLF can be prepared by genetic engineering and other technologies.
The functional mechanism of APLF includes interaction with other molecules.
APLF plays an important role in DNA repair, apoptosis, cell cycle and other processes.
APLF may be a potential prognostic marker in tumor prognosis and needs to be further validated.
APLF may have synergistic effects on drug therapy.
APLF is related to signal transduction pathways such as PI3K-Akt signaling pathway and NF-κB signaling pathway.
APLF is associated with certain cancers, immune deficiency diseases and other diseases.
The structural characteristics of APLF s include the presence of nucleotide binding sites.
APLF may play an important role in cell apoptosis.
Customer Reviews (4)
Write a reviewThe strip shape of APLF in Western blot is regular, indicating that it has excellent uniformity and predictability.
After using APLF, the sensitivity of the experiment was significantly improved.
The production process of APLF fully reflects the concept of green and environmental protection and contributes to sustainable development.
It can maintain stable performance even after multiple uses, which makes me more confident in the experimental results.
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