Recombinant Full Length Human ARL4A Protein, GST-tagged
Cat.No. : | ARL4A-1107HF |
Product Overview : | Human ARL4A full-length ORF ( AAH01111, 1 a.a. - 200 a.a.) recombinant protein with GST-tag at N-terminal. |
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Description : | ADP-ribosylation factor-like 4A is a member of the ADP-ribosylation factor family of GTP-binding proteins. ARL4A is similar to ARL4C and ARL4D and each has a nuclear localization signal and an unusually high guaninine nucleotide exchange rate. ARL4A is located in both the nuclear and extranuclear cell compartments. Multiple transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008] |
Source : | In Vitro Cell Free System |
Species : | Human |
Tag : | GST |
Molecular Mass : | 47.74 kDa |
Protein Length : | 200 amino acids |
AA Sequence : | MGNGLSDQTS ILSNLPSFQS FHIVILGLDC AGKTTVLYRL QFNEFVNTVP TKGFNTEKIK VTLGNSKTVT FHFWDVGGQE KLRPLWKSYT RCTDGIVFVV DSVDVERMEE AKTELHKITR ISENQGVPVL IVANKQDLRN SLSLSEIEKL LAMGELSSST PWHLQPTCAI IGDGLKEGLE KLHDMIIKRR KMLRQQKKKR |
Applications : | Enzyme-linked Immunoabsorbent Assay; Western Blot (Recombinant protein); Antibody Production; Protein Array |
Storage : | Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing. |
Storage Buffer : | 50 mM Tris-HCl, 10 mM reduced Glutathione, pH=8.0 in the elution buffer. |
Gene Name : | ARL4A ADP-ribosylation factor-like 4A [ Homo sapiens ] |
Official Symbol : | ARL4A |
Synonyms : | ARL4A; ADP-ribosylation factor-like 4A; ADP ribosylation factor like 4 , ARL4; ADP-ribosylation factor-like protein 4A; ADP-ribosylation factor-like 4; ARL4 |
Gene ID : | 10124 |
mRNA Refseq : | NM_001037164 |
Protein Refseq : | NP_001032241 |
MIM : | 604786 |
UniProt ID : | P40617 |
Products Types
◆ Recombinant Protein | ||
ARL4A-3602H | Recombinant Human ARL4A, His-tagged | +Inquiry |
ARL4A-439R | Recombinant Rat ARL4A Protein, His (Fc)-Avi-tagged | +Inquiry |
ARL4A-230R | Recombinant Rhesus Macaque ARL4A Protein, His (Fc)-Avi-tagged | +Inquiry |
ARL4A-722M | Recombinant Mouse ARL4A Protein, His (Fc)-Avi-tagged | +Inquiry |
ARL4A-401R | Recombinant Rhesus monkey ARL4A Protein, His-tagged | +Inquiry |
◆ Lysates | ||
ARL4A-8713HCL | Recombinant Human ARL4A 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (6)
Ask a questionMutations in the ARL4A gene have not been extensively studied. However, some studies have suggested its potential involvement in cancer progression and metastasis. Further research is required to fully understand any disease associations or potential therapeutic implications.
Dysregulation of ARL4A expression has been implicated in various pathological conditions. Alterations in its expression levels or activity may contribute to abnormalities in vesicular trafficking, cytoskeletal organization, and overall cellular homeostasis.
Yes, ARL4A interacts with several proteins to regulate various cellular processes. It can interact with GTPase-activating proteins (GAPs), guanine nucleotide exchange factors (GEFs), and effector proteins involved in vesicle trafficking and cytoskeletal dynamics.
ARL4A itself is not considered a signaling molecule in canonical signaling pathways. However, it may modulate the activity of certain signaling molecules by regulating their intracellular transport or localization.
ARL4A is generally expressed in a wide range of tissues and cell types, indicating its ubiquitous nature. Its expression may vary in different tissues and developmental stages.
The therapeutic potential of targeting ARL4A is currently being explored. Its involvement in cellular processes and potential role in diseases make it a potential therapeutic target. However, further research is needed to fully understand its mechanisms and implications for targeted therapeutics.
Customer Reviews (8)
Write a reviewThe versatility of the ARL4A protein makes it a valuable asset in my research.
The ARL4A protein is renowned for its exceptional quality, making it a perfect match for my experimental requirements.
the ARL4A protein exhibits superior performance across a range of experimental applications.
In addition to its high-quality attributes, the manufacturer of the ARL4A protein offers exemplary technical support.
Its superior purity and stability ensure reliable and accurate results, instilling confidence in my research.
Whether I am studying protein interactions, cellular localization, or signaling pathways, the ARL4A protein consistently delivers reliable and reproducible data, enabling significant scientific advancements.
Its versatility allows for its successful implementation in diverse areas such as molecular biology, cellular assays, and protein-protein interactions.
Their assistance has been invaluable in streamlining my experiments and overcoming obstacles effectively.
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