Recombinant Full Length Human ARSG Protein, C-Flag-tagged

• Cat.No.: ARSG-2059HFL
• Product Overview: Recombinant Full Length Human ARSG Protein, fused to Flag-tag at C-terminus, was expressed in Mammalian cells.

Specification

• Description: The protein encoded by this gene belongs to the sulfatase enzyme family. Sulfatases hydrolyze sulfate esters from sulfated steroids, carbohydrates, proteoglycans, and glycolipids. They are involved in hormone biosynthesis, modulation of cell signaling, and degradation of macromolecules. This protein displays arylsulfatase activity at acidic pH, as is typical of lysosomal sulfatases, and has been shown to localize in the lysosomes. Alternatively spliced transcript variants have been found for this gene.
• Source: Mammalian cells
• Species: Human
• Tag: Flag
• Form: 25 mM Tris HCl, pH 7.3, 100 mM glycine, 10% glycerol.
• Molecular Mass: 56.9 kDa
• AA Sequence: MGWLFLKVLLAGVSFSGFLYPLVDF CISGKTRGQKPNFVIILADDMGWGD LGANWAETKDTANLDKMASE GMRFVDFHAAASTCSPSRASLLTGR LGLRNGVTRNFAVTSVGGLPLNETT LAEVLQQAGYVTGIIGKWHL GHHGSYHPNFRGFDYYFGIPYSHDM GCTDTPGYNHPPCPACPQGDGPSRN LQRDCYTDVALPLYENLNIV EQPVNLSSLAQKYAEKATQFIQRAS TSGRPFLLYVALAHMHVPLPVTQLP AAPRGRSLYGAGLWEMDSLV GQIKDKVDHTVKENTFLWFTGDNGP WAQKCELAGSVGPFTGFWQTRQGGS PAKQTTWEGGHRVPALAYWP GRVPVNVTSTALLSVLDIFPTVVAL AQASLPQGRRFDGVDVSEVLFGRSQ PGHRVLFHPNSGAAGEFGAL QTVRLERYKAFYITGGARACDGSTG PELQHKFPLIFNLEDDTAEAVPLER GGAEYQAVLPEVRKVLADVL QDIANDNISSADYTQDPSVTPCCNP YQIACRCQAA TRTRPLEQKLISEEDLAANDILDYK DDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining.
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade.
• Concentration: >50 ug/mL as determined by microplate BCA method.
• Preparation: Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
• Protein Families: Druggable Genome
• Protein Pathways: Lysosome

Gene Information

• Gene Name: ARSG arylsulfatase G [ Homo sapiens (human) ]
• Official Symbol: ARSG
• Synonyms: USH4
• Gene ID: 22901
• mRNA Refseq: NM_014960.5
• Protein Refseq: NP_055775.2
• MIM: 610008
• UniProt ID: Q96EG1

Reviews

07/26/2017

Its superior purity and stability ensure reliable and reproducible results, providing me with confidence in the integrity of my experiments.

06/20/2017

Whether I am investigating protein-protein interactions, studying enzymatic activity, or conducting protein structure analyses, the ARSG protein consistently delivers exceptional performance and accurate results.

02/03/2016

The ARSG protein is an exceptional product that meets the highest standards of quality, making it an ideal choice to fulfill my experimental requirements.

Q&As

Are there any diseases associated with mutations in the ARSG gene?

Currently, there are no known diseases directly associated with mutations in the ARSG gene. Further research is needed to determine if any mutations in this gene can cause specific health conditions.

Can ARSG be used as a therapeutic target?

Currently, there are no therapeutic strategies directly targeting ARSG due to limited knowledge of its function and disease associations. However, further research on its role in sulfated molecule metabolism may identify potential therapeutic applications in the future.

Is there any evidence linking ARSG to cancer?

There is limited scientific evidence linking ARSG to cancer. However, some studies have indicated its altered expression in certain cancer types, suggesting a potential association. Further research is necessary to understand the significance of ARSG in cancer development and progression.

Are there any known interacting proteins or pathways associated with ARSG?

The specific interacting proteins or pathways associated with ARSG are currently not well-established. Further research is required to understand its potential interactions and pathways in cellular processes.

Are there any known genetic variations in the ARSG gene?

Yes, genetic variations or single nucleotide polymorphisms (SNPs) have been identified in the ARSG gene. These variations may have implications for protein function, but their exact significance and impact on health are not yet fully understood.

Is there any ongoing research in relation to the ARSG protein?

While research on the ARSG protein is limited, ongoing studies aim to elucidate its biological function, substrate specificity, and potential roles in various cellular processes. Additionally, investigations may focus on understanding the consequences of ARSG mutations and exploring therapeutic strategies for related diseases, if any are identified in the future.