Recombinant Full Length Human ATIC Protein, C-Flag-tagged
Cat.No. : | ATIC-1689HFL |
Product Overview : | Recombinant Full Length Human ATIC Protein, fused to Flag-tag at C-terminus, was expressed in Mammalian cells. |
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Description : | This gene encodes a bifunctional protein that catalyzes the last two steps of the de novo purine biosynthetic pathway. The N-terminal domain has phosphoribosylaminoimidazolecarboxamide formyltransferase activity, and the C-terminal domain has IMP cyclohydrolase activity. A mutation in this gene results in AICA-ribosiduria. |
Source : | Mammalian cells |
Species : | Human |
Tag : | Flag |
Form : | 25 mM Tris HCl, pH 7.3, 100 mM glycine, 10% glycerol. |
Molecular Mass : | 64.4 kDa |
AA Sequence : | MAPGQLALFSVSDKTGLVEFARNLT ALGLNLVASGGTAKALRDAGLAVRD VSELTGFPEMLGGRVKTLHP AVHAGILARNIPEDNADMARLDFNL IRVVACNLYPFVKTVASPGVTVEEA VEQIDIGGVTLLRAAAKNHA RVTVVCEPEDYVVVSTEMQSSESKD TSLETRRQLALKAFTHTAQYDEAIS DYFRKQYSKGVSQMPLRYGM NPHQTPAQLYTLQPKLPITVLNGAP GFINLCDALNAWQLVKELKEALGIP AAASFKHVSPAGAAVGIPLS EDEAKVCMVYDLYKTLTPISAAYAR ARGADRMSSFGDFVALSDVCDVPTA KIISREVSDGIIAPGYEEEA LTILSKKKNGNYCVLQMDQSYKPDE NEVRTLFGLHLSQKRNNGVVDKSLF SNVVTKNKDLPESALRDLIV ATIAVKYTQSNSVCYAKNGQVIGIG AGQQSRIHCTRLAGDKANYWWLRHH PQVLSMKFKTGVKRAEISNA IDQYVTGTIGEDEDLIKWKALFEEV PELLTEAEKKEWVEKLTEVSISSDA FFPFRDNVDRAKRSGVAYIA APSGSAADKVVIEACDELGIILAHT NLRLFHHTRTRPLEQKLISEEDLAA NDILDYKDDDDKV |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining. |
Stability : | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
Storage : | Store at -80 centigrade. |
Concentration : | >50 ug/mL as determined by microplate BCA method. |
Preparation : | Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps. |
Protein Families : | Stem cell - Pluripotency |
Protein Pathways : | Metabolic pathways, One carbon pool by folate, Purine metabolism |
Gene Name : | ATIC 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase [ Homo sapiens (human) ] |
Official Symbol : | ATIC |
Synonyms : | PURH; AICAR; AICARFT; IMPCHASE; HEL-S-70p |
Gene ID : | 471 |
mRNA Refseq : | NM_004044.7 |
Protein Refseq : | NP_004035.2 |
MIM : | 601731 |
UniProt ID : | P31939 |
Products Types
◆ Recombinant Protein | ||
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Atic-365M | Recombinant Mouse Atic Protein, MYC/DDK-tagged | +Inquiry |
ATIC-398H | Recombinant Human ATIC Protein, His (Fc)-Avi-tagged | +Inquiry |
ATIC-831M | Recombinant Mouse ATIC Protein, His (Fc)-Avi-tagged | +Inquiry |
ATIC-2090M | Recombinant Mouse ATIC Protein | +Inquiry |
◆ Lysates | ||
ATIC-8618HCL | Recombinant Human ATIC 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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