Recombinant Full Length Human BAG3 Protein, C-Flag-tagged
Cat.No. : | BAG3-343HFL |
Product Overview : | Recombinant Full Length Human BAG3 Protein, fused to Flag-tag at C-terminus, was expressed in Mammalian cells. |
- Specification
- Gene Information
- Related Products
Description : | BAG proteins compete with Hip for binding to the Hsc70/Hsp70 ATPase domain and promote substrate release. All the BAG proteins have an approximately 45-amino acid BAG domain near the C terminus but differ markedly in their N-terminal regions. The protein encoded by this gene contains a WW domain in the N-terminal region and a BAG domain in the C-terminal region. The BAG domains of BAG1, BAG2, and BAG3 interact specifically with the Hsc70 ATPase domain in vitro and in mammalian cells. All 3 proteins bind with high affinity to the ATPase domain of Hsc70 and inhibit its chaperone activity in a Hip-repressible manner. |
Source : | Mammalian cells |
Species : | Human |
Tag : | Flag |
Form : | 25 mM Tris HCl, pH 7.3, 100 mM glycine, 10% glycerol. |
Molecular Mass : | 61.4 kDa |
AA Sequence : | MSAATHSPMMQVASGNGDRDPLPPG WEIKIDPQTGWPFFVDHNSRTTTWN DPRVPSEGPKETPSSANGPS REGSRLPPAREGHPVYPQLRPGYIP IPVLHEGAENRQVHPFHVYPQPGMQ RFRTEAAAAAPQRSQSPLRG MPETTQPDKQCGQVAAAAAAQPPAS HGPERSQSPAASDCSSSSSSASLPS SGRSSLGSHQLPRGYISIPV IHEQNVTRPAAQPSFHQAQKTHYPA QQGEYQTHQPVYHKIQGDDWEPRPL RAASPFRSSVQGASSREGSP ARSSTPLHSPSPIRVHTVVDRPQQP MTHRETAPVSQPENKPESKPGPVGP ELPPGHIPIQVIRKEVDSKP VSQKPPPPSEKVEVKVPPAPVPCPP PSPGPSAVPSSPKSVATEERAAPST APAEATPPKPGEAEAPPKHP GVLKVEAILEKVQGLEQAVDNFEGK KTDKKYLMIEEYLTKELLALDSVDP EGRADVRQARRDGVRKVQTI LEKLEQKAIDVPGQVQVYELQPSNL EADQPLQAIMEMGAVAADKGKKNAG NAEDPHTETQQPEATAAATS NPSSMTDTPGNPAAPTRTRPLEQKL ISEEDLAANDILDYKDDDDKV |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining. |
Stability : | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
Storage : | Store at -80 centigrade. |
Concentration : | >50 ug/mL as determined by microplate BCA method. |
Preparation : | Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps. |
Protein Families : | Druggable Genome |
Gene Name : | BAG3 BAG cochaperone 3 [ Homo sapiens (human) ] |
Official Symbol : | BAG3 |
Synonyms : | BIS; MFM6; BAG-3; CAIR-1 |
Gene ID : | 9531 |
mRNA Refseq : | NM_004281.4 |
Protein Refseq : | NP_004272.2 |
MIM : | 603883 |
UniProt ID : | O95817 |
Products Types
◆ Recombinant Protein | ||
BAG3-2138H | Recombinant Human BAG3 Protein, MYC/DDK-tagged | +Inquiry |
BAG3-952M | Recombinant Mouse BAG3 Protein, His (Fc)-Avi-tagged | +Inquiry |
BAG3-335R | Recombinant Rhesus Macaque BAG3 Protein, His (Fc)-Avi-tagged | +Inquiry |
BAG3-293H | Recombinant Human BAG3 Protein, His-tagged | +Inquiry |
Bag3-1817M | Recombinant Mouse Bag3 Protein, Myc/DDK-tagged | +Inquiry |
◆ Lysates | ||
BAG3-56HCL | Recombinant Human BAG3 lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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