Recombinant Full Length Human BAIAP2 Protein, GST-tagged
Cat.No. : | BAIAP2-1806HF |
Product Overview : | Human BAIAP2 full-length ORF ( AAH32559, 1 a.a. - 512 a.a.) recombinant protein with GST-tag at N-terminal. |
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Description : | The protein encoded by this gene has been identified as a brain-specific angiogenesis inhibitor (BAI1)-binding protein. This adaptor protein links membrane bound G-proteins to cytoplasmic effector proteins. This protein functions as an insulin receptor tyrosine kinase substrate and suggests a role for insulin in the central nervous system. It also associates with a downstream effector of Rho small G proteins, which is associated with the formation of stress fibers and cytokinesis. This protein is involved in lamellipodia and filopodia formation in motile cells and may affect neuronal growth-cone guidance. This protein has also been identified as interacting with the dentatorubral-pallidoluysian atrophy gene, which is associated with an autosomal dominant neurodegenerative disease. Alternative splicing results in multiple transcript variants encoding distinct isoforms |
Source : | In Vitro Cell Free System |
Species : | Human |
Tag : | GST |
Form : | 50 mM Tris-HCl, 10 mM reduced Glutathione, pH=8.0 in the elution buffer. |
Molecular Mass : | 82.06 kDa |
Protein Length : | 512 amino acids |
AA Sequence : | MSLSRSEEMHRLTENVYKTIMEQFN PSLRNFIAMGKNYEKALAGVTYAAK GYFDALVKMGELASESQGSKELGDV LFQMAEVHRQIQNQLEEMLKSFHNE LLTQLEQKVELDSRYLSAALKKYQT EQRSKGDALDKCQAELKKLRKKSQG SKNPQKYSDKELQYIDAISNKQGEL ENYVSDGYKTALTEERRRFCFLVEK QCAVAKNSAAYHSKGKELLAQKLPL WQQACADPSKIPERAVQLMQQVASN GATLPSALSASKSNLVISDPIPGAK PLPVPPELAPFVGRMSAQESTPIMN GVTGPDGEDYSPWADRKAAQPKSLS PPQSQSKLSDSYSNTLPVRKSVTPK NSYATTENKTLPRSSSMAAGLERNG RMRVKAIFSHAAGDNSTLLSFKEGD LITLLVPEARDGWHYGESEKTKMRG WFPFSYTRVLDSDGSDRLHMSLQQG KSSSTGNLLDKDDLAIPPPDYGAAS RAFPAQTASGFKQRPYSVAVPAFSQ GLDDYGARSMSR |
Notes : | Best use within three months from the date of receipt of this protein. |
Storage : | Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing. |
Storage Buffer : | 50 mM Tris-HCl, 10 mM reduced Glutathione, pH=8.0 in the elution buffer. |
Gene Name : | BAIAP2 BAI1-associated protein 2 [ Homo sapiens ] |
Official Symbol : | BAIAP2 |
Synonyms : | BAIAP2; BAI1-associated protein 2; brain-specific angiogenesis inhibitor 1-associated protein 2; BAP2; IRS-58; IRSp53/58; fas ligand-associated factor 3; insulin receptor substrate p53/p58; insulin receptor substrate protein of 53 kDa; FLAF3; IRSP53 |
Gene ID : | 10458 |
mRNA Refseq : | NM_001144888 |
Protein Refseq : | NP_001138360 |
MIM : | 605475 |
UniProt ID : | Q9UQB8 |
Products Types
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◆ Lysates | ||
BAIAP2-8522HCL | Recombinant Human BAIAP2 293 Cell Lysate | +Inquiry |
BAIAP2-8521HCL | Recombinant Human BAIAP2 293 Cell Lysate | +Inquiry |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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