Recombinant Full Length Human BBC3 Protein, C-Flag-tagged
Cat.No. : | BBC3-558HFL |
Product Overview : | Recombinant Full Length Human BBC3 Protein, fused to Flag-tag at C-terminus, was expressed in Mammalian cells. |
- Specification
- Gene Information
- Related Products
Description : | This gene encodes a member of the BCL-2 family of proteins. This family member belongs to the BH3-only pro-apoptotic subclass. The protein cooperates with direct activator proteins to induce mitochondrial outer membrane permeabilization and apoptosis. It can bind to anti-apoptotic Bcl-2 family members to induce mitochondrial dysfunction and caspase activation. Because of its pro-apoptotic role, this gene is a potential drug target for cancer therapy and for tissue injury. Alternative splicing results in multiple transcript variants. |
Source : | Mammalian cells |
Species : | Human |
Tag : | Flag |
Form : | 25 mM Tris HCl, pH 7.3, 100 mM glycine, 10% glycerol. |
Molecular Mass : | 20.4 kDa |
AA Sequence : | MARARQEGSSPEPVEGLARDGPRPF PLGRLVPSAVSCGLCEPGLAAAPAA PTLLPAAYLCAPTAPPAVTA ALGGSRWPGGPRSRPRGPRPDGPQP SLSLAEQHLESPVPSAPGALAGGPT QAAPGVRGEEEQWAREIGAQ LRRMADDLNAQYERRRQEEQQRHRP SPWRVLYNLIMGLLPLPRGHRAPEM EPNTRTRPLEQKLISEEDLAANDIL DYKDDDDKV |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining. |
Stability : | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
Storage : | Store at -80 centigrade. |
Concentration : | >50 ug/mL as determined by microplate BCA method. |
Preparation : | Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps. |
Protein Families : | Druggable Genome |
Protein Pathways : | Huntington's disease, p53 signaling pathway |
Gene Name : | BBC3 BCL2 binding component 3 [ Homo sapiens (human) ] |
Official Symbol : | BBC3 |
Synonyms : | JFY1; PUMA; JFY-1 |
Gene ID : | 27113 |
mRNA Refseq : | NM_014417.5 |
Protein Refseq : | NP_055232.1 |
MIM : | 605854 |
UniProt ID : | Q9BXH1 |
Products Types
◆ Recombinant Protein | ||
BBC3-604R | Recombinant Rat BBC3 Protein, His (Fc)-Avi-tagged | +Inquiry |
Bbc3-1827M | Recombinant Mouse Bbc3 Protein, Myc/DDK-tagged | +Inquiry |
BBC3-427H | Recombinant Human BBC3 Protein, His (Fc)-Avi-tagged | +Inquiry |
BBC3-4413Z | Recombinant Zebrafish BBC3 | +Inquiry |
BBC3-26H | Recombinant Human BBC3 protein, His-tagged | +Inquiry |
◆ Lysates | ||
BBC3-8505HCL | Recombinant Human BBC3 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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