Recombinant Full Length Human BNIPL Protein, GST-tagged

• Cat.No.: BNIPL-3760HF
• Product Overview: Human BNIPL full-length ORF ( AAH27868, 1 a.a. - 275 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: This gene reduces the metastatic potential, but not the tumorogenicity, of human breast cancer and melanoma cell lines. The protein encoded by this gene localizes primarily to the nucleus and is a component of the mSin3a family of histone deacetylase complexes (HDAC). The protein contains two coiled-coil motifs and several imperfect leucine zipper motifs. Alternative splicing results in two transcript variants encoding different isoforms.
• Source: In Vitro Cell Free System
• Species: Human
• Tag: GST
• Form: 50 mM Tris-HCl, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
• Molecular Mass: 55.99 kDa
• Protein Length: 275 amino acids
• AA Sequence: MRKRLSAPELRLSLTKGPGNDGASP TQSAPSSPDGSSDLEIDELETPSDS EQLDSGHEFEWEDELPRAEGLGTSE TAERLGRGCMWDVTGEDGHHWRVFR MGPREQRVDMTVIEPYKKVLSHGGY HGDGLNAVILFASCYLPRSSIPNYT YVMEHLFRYMVGTLELLVAENYLLV HLSGGTSRAQVPPLSWIRQCYRTLD RRLRKNLRALVVVHATWYVKAFLAL LRPFISSKFTRKIRFLDSLGELAQL ISLDQVHIPEAVRQLDRDLHGSGGT
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCl, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: BNIPL BCL2/adenovirus E1B 19kD interacting protein like [ Homo sapiens ]
• Official Symbol: BNIPL
• Synonyms: BNIPL; BCL2/adenovirus E1B 19kD interacting protein like; bcl-2/adenovirus E1B 19 kDa-interacting protein 2-like protein; BNIPl 1; BNIPL 2; PP753; BNIP-2 similar; BNIP-S; BNIPL-1; BNIPL-2
• Gene ID: 149428
• mRNA Refseq: NM_001159642
• Protein Refseq: NP_001153114
• MIM: 611275
• UniProt ID: Q7Z465