Description : |
Calpains are a family of cytosolic calcium-activated cysteine proteases involved in a variety of cellular processes including apoptosis, cell division, modulation of integrin-cytoskeletal interactions, and synaptic plasticity (Dear et al., 2000 [PubMed 10964513]). CAPN14 belongs to the calpain large subunit family. |
Source : |
In Vitro Cell Free System |
Species : |
Human |
Tag : |
GST |
Form : |
50 mM Tris-HCl, 10 mM reduced Glutathione, pH=8.0 in the elution buffer. |
Molecular Mass : |
85.4 kDa |
Protein Length : |
508 amino acids |
AA Sequence : |
MLASSGSGLSGSYEDLQSGQVSEAL VDFTGGVTMTINLAEAHGNLWDILI EATYNRTLIGCQTHSGEKILENGLV EGHAYTLTGIRKVTCKHRPEYLVKL RNPWGKVEWKGDWSDSSSKWELLSP KEKILLLRKDNDGEFWMTLQDFKTH FVLLVICKLTPGLLSQEAAQKWTYT MREGRWEKRSTAGGQRQLLQDTFWK NPQFLLSVWRPEEGRRSLRPCSVLV SLLQKPRHRCRKRKPLLAIGFYLYR MNKYHDDQRRLPPEFFQRNTPLSQP DRFLKEKEVSQELCLEPGTYLIVPC ILEAHQKSEFVLRVFSRKHIFYEIG SNSGVVFSKEIEDQNERQDEFFTKF FEKHPEINAVQLQNLLNQMTWSSLG SRQPFFSLEACQGILALLDLNASGT MSIQEFRDLWKQLKLSQKVFHKQDR GSGYLNWEQLHAAMREAGIMLSDDV CQLMLIRYGGPRLQMDFVSFIHLML RVENMEDVFQNLTQDGKGIYLQKPE WMMMALYS |
Applications : |
Enzyme-linked Immunoabsorbent; Assay Western Blot (Recombinant protein); Antibody Production; Protein Array |
Notes : |
Best use within three months from the date of receipt of this protein. |
Storage : |
Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing. |