Recombinant Full Length Human CARM1 Protein, C-Flag-tagged

• Cat.No.: CARM1-1535HFL
• Product Overview: Recombinant Full Length Human CARM1 Protein, fused to Flag-tag at C-terminus, was expressed in Mammalian cells.

Specification

• Description: This gene belongs to the protein arginine methyltransferase (PRMT) family. The encoded enzyme catalyzes the methylation of guanidino nitrogens of arginyl residues of proteins. The enzyme acts specifically on histones and other chromatin-associated proteins and is involved in regulation of gene expression. The enzyme may act in association with other proteins or within multi-protein complexes and may play a role in cell type-specific functions and cell lineage specification. A related pseudogene is located on chromosome 9.
• Source: Mammalian cells
• Species: Human
• Tag: Flag
• Form: 25 mM Tris HCl, pH 7.3, 100 mM glycine, 10% glycerol.
• Molecular Mass: 65.7 kDa
• AA Sequence: MAAAAAAVGPGAGGAGSAVPGGAGP CATVSVFPGARLLTIGDANGEIQRH AEQQALRLEVRAGPDSAGIA LYSHEDVCVFKCSVSRETECSRVGK QSFIITLGCNSVLIQFATPNDFCSF YNILKTCRGHTLERSVFSER TEESSAVQYFQFYGYLSQQQNMMQD YVRTGTYQRAILQNHTDFKDKIVLD VXLWLWDPVVFCRPSWSTEN LRGXRPAPWPSTXEVLVKSNNLTDR IVVIPGKVXGXCXXPXXQVDIIXLG AHGLHALQRXACWRATSTPX KYLKPSGNMFPTIGDVHLAPFTDEQ LYMEQFTKANFWYQPSFHGVDLSAL RGAAVDEYFRQPVVDTFDIR ILMAKSVKYTVNFLEAKEGDLHRIE IPFKFHMLHSGLVHGLAFWFDVAFI GSIMTVWLSTAPTEPLTHWY QVRCLFQSPLFAKAGDTLSGTCLLI ANKRQSYDISIVAQVDQTGSKSSNL LDLKNPFFRYTGTTPSPPPG SHYTSPSENMWNTGSTYNLSSGMAV AGMPTAYDLSSVIASGSSVGHNNLI PLANTGIVNHTHSRMGSIMS
  TGIVQGSSGAQGSGGGSTSAHYAVN SQFTMGGPAISMASPMSIPTNTMHY GSTRTRPLEQKLISEEDLAANDILD YKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining.
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade.
• Concentration: >50 ug/mL as determined by microplate BCA method.
• Preparation: Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
• Protein Families: Druggable Genome, Transcription Factors

Gene Information

• Gene Name: CARM1 coactivator associated arginine methyltransferase 1 [ Homo sapiens (human) ]
• Official Symbol: CARM1
• Synonyms: PRMT4
• Gene ID: 10498
• mRNA Refseq: NM_199141.2
• Protein Refseq: NP_954592.1
• MIM: 603934
• UniProt ID: Q86X55