Recombinant Full Length Human CD36 Protein, C-Flag-tagged

• Cat.No.: CD36-39HFL
• Product Overview: Recombinant Full Length Human CD36 Protein, fused to Flag-tag at C-terminus, was expressed in Mammalian cells.

Specification

• Description: The protein encoded by this gene is the fourth major glycoprotein of the platelet surface and serves as a receptor for thrombospondin in platelets and various cell lines. Since thrombospondins are widely distributed proteins involved in a variety of adhesive processes, this protein may have important functions as a cell adhesion molecule. It binds to collagen, thrombospondin, anionic phospholipids and oxidized LDL. It directly mediates cytoadherence of Plasmodium falciparum parasitized erythrocytes and it binds long chain fatty acids and may function in the transport and/or as a regulator of fatty acid transport. Mutations in this gene cause platelet glycoprotein deficiency. Multiple alternatively spliced transcript variants have been found for this gene.
• Source: Mammalian cells
• Species: Human
• Tag: Flag
• Form: 25 mM Tris HCl, pH 7.3, 100 mM glycine, 10% glycerol.
• Molecular Mass: 52.9 kDa
• AA Sequence: MGCDRNCGLIAGAVIGAVLAVFGGI LMPVGDLLIQKTIKKQVVLEEGTIA FKNWVKTGTEVYRQFWIFDV QNPQEVMMNSSNIQVKQRGPYTYRV RFLAKENVTQDAEDNTVSFLQPNGA IFEPSLSVGTEADNFTVLNL AVAAASHIYQNQFVQMILNSLINKS KSSMFQVRTLRELLWGYRDPFLSLV PYPVTTTVGLFYPYNNTADG VYKVFNGKDNISKVAIIDTYKGKRN LSYWESHCDMINGTDAASFPPFVEK SQVLQFFSSDICRSIYAVFE SDVNLKGIPVYRFVLPSKAFASPVE NPDNYCFCTEKIISKNCTSYGVLDI SKCKEGRPVYISLPHFLYAS PDVSEPIDGLNPNEEEHRTYLDIEP ITGFTLQFAKRLQVNLLVKPSEKIQ VLKNLKRNYIVPILWLNETG
  TIGDEKANMFRSQVTGKINLLGLIE MILLSVGVVMFVAFMISYCACRSKT IKTRTRPLEQKLISEEDLAANDILD YKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining.
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade.
• Concentration: >50 ug/mL as determined by microplate BCA method.
• Preparation: Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
• Protein Families: Druggable Genome, Transmembrane
• Protein Pathways: Adipocytokine signaling pathway, ECM-receptor interaction, Hematopoietic cell lineage, PPAR signaling pathway

Gene Information

• Gene Name: CD36 CD36 molecule [ Homo sapiens (human) ]
• Official Symbol: CD36
• Synonyms: FAT; GP4; GP3B; GPIV; CHDS7; PASIV; SCARB3; BDPLT10
• Gene ID: 948
• mRNA Refseq: NM_001001548.3
• Protein Refseq: NP_001001548.1
• MIM: 173510
• UniProt ID: P16671