Recombinant Full Length Human CDH2 Protein, C-Flag-tagged

• Cat.No.: CDH2-877HFL
• Product Overview: Recombinant Full Length Human CDH2 Protein, fused to Flag-tag at C-terminus, was expressed in Mammalian cells.

Specification

• Description: This gene encodes a classical cadherin and member of the cadherin superfamily. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein is proteolytically processed to generate a calcium-dependent cell adhesion molecule and glycoprotein. This protein plays a role in the establishment of left-right asymmetry, development of the nervous system and the formation of cartilage and bone.
• Source: Mammalian cells
• Species: Human
• Tag: Flag
• Form: 25 mM Tris HCl, pH 7.3, 100 mM glycine, 10% glycerol.
• Molecular Mass: 97.2 kDa
• AA Sequence: MCRIAGALRTLLPLLAALLQASVEA SGEIALCKTGFPEDVYSAVLSKDVH EGQPLLNVKFSNCNGKRKVQ YESSEPADFKVDEDGMVYAVRSFPL SSEHAKFLIYAQDKETQEKWQVAVK LSLKPTLTEESVKESAEVEE IVFPRQFSKHSGHLQRQKRDWVISP INLPENSRGPFPQELVRIRSDRDKN LSLRYSVTGPGADQPPTGIF IINPISGQLSVTKPLDREQIARFHL RAHAVDINGNQVENPIDIVINVIDM NDNRPEFLHQVWNGTVPEGS KPGTYVMTVTAIDADDPNALNGMLR YRIVSQAPSTPSPNMFTINNETGDI ITVAAGLDREKVQQYTLIIQ ATDMEGNPTYGLSNTATAVITVTDV NDNPPEFTAMTFYGEVPENRVDIIV ANLTVTDKDQPHTPAWNAVY RISGGDPTGRFAIQTDQNSNDGLVT VVKPIDFEANRMFVLTVAAENQVPL AKGIQHPPQSTATMSVTVID VNENPYFAPNPKIIRQEEGLHAGTM LTTFTAQDPDRYMQQNIRYTKLSDP ANWLKIDPVNGQITTIAVLD RESPNVKNNIYNATFLASDNGIPPM SGTGTLQIYLLDINDNAPQVLPQEA ETCETPDPNSINITALDYGI DPNAGPFAFDLPLSPVTIKRNWTIT RLNGDFAQLNLKIKFLEAGIYEVPI IITDSGNPPKSNISILRVKV CQCDSNGDCTDVDRIVGAGLGTGAI IAILLCIIILLILVLMFVVWMKRRD KERQAKQLLIDPEDDVRDNI LKYDEEGGGEEDQDYDLSQLQQPDT VEPDAIKPVGIRRMDERPIHAEPQY PVRSAAPHPGDIGDFINEGL KAADNDPTAPPYDSLLVFDYEGSGS TAGSLSSLNSSSSGGEQDYDYLNDW GPRFKKLADMYGGGDDTRTRPLEQK LISEEDLAANDILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining.
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade.
• Concentration: >50 ug/mL as determined by microplate BCA method.
• Preparation: Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
• Protein Families: Druggable Genome, ES Cell Differentiation/IPS, Transmembrane
• Protein Pathways: Arrhythmogenic right ventricular cardiomyopathy (ARVC), Cell adhesion molecules (CAMs)

Gene Information

• Gene Name: CDH2 cadherin 2 [ Homo sapiens (human) ]
• Official Symbol: CDH2
• Synonyms: CDHN; NCAD; ACOGS; ADHD8; CD325; ARVD14; CDw325
• Gene ID: 1000
• mRNA Refseq: NM_001792.5
• Protein Refseq: NP_001783.2
• MIM: 114020
• UniProt ID: P19022