Recombinant Full Length Human CFD Protein, GST-tagged
Cat.No. : | CFD-2479HF |
Product Overview : | Human DF full-length ORF ( NP_001919.2, 1 a.a. - 253 a.a.) recombinant protein with GST-tag at N-terminal. |
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Description : | This gene encodes a member of the S1, or chymotrypsin, family of serine peptidases. This protease catalyzes the cleavage of factor B, the rate-limiting step of the alternative pathway of complement activation. This protein also functions as an adipokine, a cell signaling protein secreted by adipocytes, which regulates insulin secretion in mice. Mutations in this gene underlie complement factor D deficiency, which is associated with recurrent bacterial meningitis infections in human patients. Alternative splicing of this gene results in multiple transcript variants. At least one of these variants encodes a preproprotein that is proteolytically processed to generate the mature protease. [provided by RefSeq, Nov 2015] |
Source : | In Vitro Cell Free System |
Species : | Human |
Tag : | GST |
Molecular Mass : | 53.4 kDa |
Protein Length : | 253 amino acids |
AA Sequence : | MHSWERLAVLVLLGAAACAAPPRGR ILGGREAEAHARPYMASVQLNGAHL CGGVLVAEQWVLSAAHCLEDAADGK VQVLLGAHSLSQPEPSKRLYDVLRA VPHPDSQPDTIDHDLLLLQLSEKAT LGPAVRPLPWQRVDRDVAPGTLCDV AGWGIVNHAGRRPDSLQHVLLPVLD RATCNRRTHHDGAITERLMCAESNR RDSCKGDSGGPLVCGGVLEGVVTSG SRVCGNRKKPGIYTRVASYAAWIDS VLA |
Applications : | Enzyme-linked Immunoabsorbent Assay Western Blot (Recombinant protein) Antibody Production Protein Array |
Notes : | Best use within three months from the date of receipt of this protein. |
Storage : | Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing. |
Storage Buffer : | 50 mM Tris-HCl, 10 mM reduced Glutathione, pH=8.0 in the elution buffer. |
Gene Name : | CFD complement factor D (adipsin) [ Homo sapiens ] |
Official Symbol : | CFD |
Synonyms : | CFD; complement factor D (adipsin); D component of complement (adipsin) , DF, PFD, properdin factor D; complement factor D; ADN; properdin factor D; C3 convertase activator; complement factor D preproprotein; D component of complement (adipsin); DF; PFD; ADIPSIN; |
Gene ID : | 1675 |
mRNA Refseq : | NM_001928 |
Protein Refseq : | NP_001919 |
MIM : | 134350 |
UniProt ID : | P00746 |
Products Types
◆ Recombinant Protein | ||
CFD-2662H | Recombinant Human CFD Protein, His (Fc)-Avi-tagged | +Inquiry |
CFD-790H | Recombinant Human CFD Protein | +Inquiry |
CFD-1083H | Recombinant Human CFD protein(Ile26-Ala253), His-tagged | +Inquiry |
CFD-760H | Recombinant Human CFD Protein, His-tagged | +Inquiry |
CFD-1165R | Recombinant Rat CFD Protein, His/MYC-tagged | +Inquiry |
◆ Native Protein | ||
CFD-348H | Active Native Human Factor D | +Inquiry |
◆ Lysates | ||
CFD-1870MCL | Recombinant Mouse CFD cell lysate | +Inquiry |
CFD-1864HCL | Recombinant Human CFD cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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