Recombinant Full Length Human CLCN2 Protein, GST-tagged

• Cat.No.: CLCN2-1967HF
• Product Overview: Human CLCN2 full-length ORF ( AAH21578.1, 38 a.a. - 387 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: This gene encodes a voltage-gated chloride channel. The encoded protein is a transmembrane protein that maintains chloride ion homeostasis in various cells. Defects in this gene may be a cause of certain epilepsies. Four transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2012]
• Source: In Vitro Cell Free System
• Species: Human
• Tag: GST
• Molecular Mass: 64.24 kDa
• Protein Length: 38-387 amino acids
• AA Sequence: TVSTAVIVFELTGQIAHILPVMIVV ILANAVAQSLQPSLYDSIIRIKKLP YLPELGWGRHQQYRVRVEDIMVRDV PHVALSCTFRDLRLALHRTKGRMLA LVESPESMILLGSIERSQVVALLGA QLSPARRRQHMQERRATQTSPLSDQ EGPPTPEASVCFQVNTEDSAFPAAR GETHKPLKPALKRGPSVTRNLGESP TGSAESAGIALRSLFCGSPPPEAAS EKLESCEKRKLKRVRISLASDADLE GEMSPEETHTIFSLLGVDHAYVTSI GRLIGIVTLKELRKAIEGSVTAQGV KVRPPLASFRDSATSSSDTETTEVH ALWGPHSRHGLPREGSPSDSDDKCQ
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCl, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: CLCN2 chloride channel, voltage-sensitive 2 [ Homo sapiens ]
• Official Symbol: CLCN2
• Synonyms: CLCN2; chloride channel, voltage-sensitive 2; chloride channel 2; chloride channel protein 2; ClC 2; CLC2; EJM6; ECA2; ECA3; EGI3; EGMA; EJM8; CIC-2; EGI11; clC-2
• Gene ID: 1181
• mRNA Refseq: NM_001171087
• Protein Refseq: NP_001164558
• MIM: 600570
• UniProt ID: P51788